Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for GPT (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2875
Official gene symbolGPT
Full nameglutamic-pyruvate transaminase (alanine aminotransferase)
Gene summaryThis gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
LocationChromosome: 8   Locus: 
Gene position145729465 - 145732555  Map Viewer
OMIM ID138200