Gene information for IGF1R (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 3480 |
Official gene symbol | IGF1R |
Full name | insulin-like growth factor 1 receptor |
Aliases | ,CD221,IGFIR,IGFR,JTK13,MGC142170,MGC142172,MGC18216, |
Gene summary | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq] |
Location | Chromosome: 15 Locus: |
Gene position | 99192761 - 99507759 Map Viewer |
OMIM ID | 147370 |