Gene information for MLLT4 (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 4301 |
Official gene symbol | MLLT4 |
Full name | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
Aliases | ,AF-6,AF6,AFADIN,FLJ34371,RP3-431P23.3, |
Gene summary | AF6 is a Ras (see HRAS; MIM 190020) target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL (MIM 159555) in leukemias caused by t(6;11) translocations (Taya et al., 1998 [PubMed 9722616]).[supplied by OMIM] |
Location | Chromosome: 6 Locus: |
Gene position | 168227671 - 168365793 Map Viewer |
OMIM ID | 159559 |