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Entrez gene ID | 4353 |
Official gene symbol | MPO |
Full name | myeloperoxidase |
Aliases | ,-, |
Gene summary | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq] |
Location | Chromosome: 17 Locus: |
Gene position | 56358296 - 56347217 Map Viewer |