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Entrez gene ID | 4520 |
Official gene symbol | MTF1 |
Full name | metal-regulatory transcription factor 1 |
Aliases | ,MGC23036,MTF-1,ZRF, |
Gene summary | This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq] |
Location | Chromosome: 1 Locus: |
Gene position | 38325292 - 38275239 Map Viewer |
OMIM ID | 600172 |