Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for PAPPA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5069
Official gene symbolPAPPA
Full namepregnancy-associated plasma protein A, pappalysin 1
Gene summaryThis gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq]
LocationChromosome: 9   Locus: 
Gene position118916071 - 119164600  Map Viewer
OMIM ID176385