Gene information for PFKFB1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
| Entrez gene ID | 5207 |
| Official gene symbol | PFKFB1 |
| Full name | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| Aliases | ,F6PK,HL2K,MGC116715,MGC116717,PFRX, |
| Gene summary | This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. [provided by RefSeq] |
| Location | Chromosome: X Locus: |
| Gene position | 55020511 - 54959590 Map Viewer |
| OMIM ID | 311790 |
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