Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for PFKFB1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5207
Official gene symbolPFKFB1
Full name6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene summaryThis gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. [provided by RefSeq]
LocationChromosome: X   Locus: 
Gene position55020511 - 54959590  Map Viewer
OMIM ID311790