Gene information for PI3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
| Entrez gene ID | 5266 |
| Official gene symbol | PI3 |
| Full name | peptidase inhibitor 3, skin-derived |
| Aliases | ,ESI,MGC13613,SKALP,WAP3,WFDC14,cementoin, |
| Gene summary | This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq] |
| Location | Chromosome: 20 Locus: |
| Gene position | 43803540 - 43805185 Map Viewer |
| OMIM ID | 182257 |
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