Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for SFRP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6422
Official gene symbolSFRP1
Full namesecreted frizzled-related protein 1
Gene summaryThis gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq]
LocationChromosome: 8   Locus: 
Gene position41166990 - 41119476  Map Viewer
OMIM ID604156