Gene information for SFRP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
| Entrez gene ID | 6422 |
| Official gene symbol | SFRP1 |
| Full name | secreted frizzled-related protein 1 |
| Aliases | ,FRP,FRP-1,FRP1,FrzA,SARP2, |
| Gene summary | This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq] |
| Location | Chromosome: 8 Locus: |
| Gene position | 41166990 - 41119476 Map Viewer |
| OMIM ID | 604156 |
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