Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for TAF2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6873
Official gene symbolTAF2
Full nameTAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
Gene summaryInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators. [provided by RefSeq]
LocationChromosome: 8   Locus: 
Gene position120845074 - 120743014  Map Viewer
OMIM ID604912