Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for TLR1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7096
Official gene symbolTLR1
Full nametoll-like receptor 1
Aliases,CD281,DKFZp547I0610,DKFZp564I0682,KIAA0012,MGC104956,MGC126311,MGC126312,TIL,TIL. LPRS5,rsc786,
Gene summaryThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq]
LocationChromosome: 4   Locus: 
Gene position38806412 - 38797876  Map Viewer
OMIM ID601194