Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for TNFRSF11A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8792
Official gene symbolTNFRSF11A
Full nametumor necrosis factor receptor superfamily, member 11a, NFKB activator
Gene summaryThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells. [provided by RefSeq]
LocationChromosome: 18   Locus: 
Gene position59992548 - 60053504  Map Viewer
OMIM ID603499