Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for SUCLA2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8803
Official gene symbolSUCLA2
Full namesuccinate-CoA ligase, ADP-forming, beta subunit
Gene summarySuccinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq]
LocationChromosome: 13   Locus: 
Gene position48575462 - 48516791  Map Viewer
OMIM ID603921