Search results for the GEO ID: GSE15913 |
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|
GSM ID | GPL ID |
Select for analysis |
Title |
Source name |
Description |
Characteristics |
GSM399720 | GPL570 |
|
CLL patient 01, untreated
|
peripheral blood derived sample of CLL patient 01 prior to therapy
|
treatment response: complete response (CR)
wbc change: -5.9
treg fold change: -2.724969843
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 01 before thalidomide treament
|
Sample_geo_accession | GSM399720
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399720/suppl/GSM399720.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399720/suppl/GSM399720.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399721 | GPL570 |
|
CLL patient 02, untreated
|
peripheral blood derived sample of CLL patient 02 prior to therapy
|
treatment response: partial response (PR)
wbc change: 27.2
treg fold change: -5.151223776
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 02 before thalidomide treament
|
Sample_geo_accession | GSM399721
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399721/suppl/GSM399721.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399721/suppl/GSM399721.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399722 | GPL570 |
|
CLL patient 03, untreated
|
peripheral blood derived sample of CLL patient 03 prior to therapy
|
treatment response: complete response (CR)
wbc change: -2.7
treg fold change: -1.55654102
flare reaction: yes
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 03 before thalidomide treament
|
Sample_geo_accession | GSM399722
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399722/suppl/GSM399722.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399722/suppl/GSM399722.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399723 | GPL570 |
|
CLL patient 04, untreated
|
peripheral blood derived sample of CLL patient 04 prior to therapy
|
treatment response: no response (NR)
wbc change: -114
treg fold change: -2.881040892
flare reaction: no
deletion 17p13: yes
deletion 11q22-q23: no
|
Gene expression data from CLL patient 04 before thalidomide treament
|
Sample_geo_accession | GSM399723
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399723/suppl/GSM399723.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399723/suppl/GSM399723.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399724 | GPL570 |
|
CLL patient 05, untreated
|
peripheral blood derived sample of CLL patient 05 prior to therapy
|
treatment response: no response (NR)
wbc change: -1.1
treg fold change: NA
flare reaction: yes
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 05 before thalidomide treament
|
Sample_geo_accession | GSM399724
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399724/suppl/GSM399724.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399724/suppl/GSM399724.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399725 | GPL570 |
|
CLL patient 06, untreated
|
peripheral blood derived sample of CLL patient 06 prior to therapy
|
treatment response: no response (NR)
wbc change: 36.1
treg fold change: -19.38718663
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 06 before thalidomide treament
|
Sample_geo_accession | GSM399725
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399725/suppl/GSM399725.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399725/suppl/GSM399725.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399726 | GPL570 |
|
CLL patient 07, untreated
|
peripheral blood derived sample of CLL patient 07 prior to therapy
|
treatment response: no response (NR)
wbc change: -30
treg fold change: -1.127659574
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 07 before thalidomide treament
|
Sample_geo_accession | GSM399726
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399726/suppl/GSM399726.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399726/suppl/GSM399726.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399727 | GPL570 |
|
CLL patient 08, untreated
|
peripheral blood derived sample of CLL patient 08 prior to therapy
|
treatment response: partial response (PR)
wbc change: 12.5
treg fold change: NA
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 08 before thalidomide treament
|
Sample_geo_accession | GSM399727
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399727/suppl/GSM399727.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399727/suppl/GSM399727.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399728 | GPL570 |
|
CLL patient 09, untreated
|
peripheral blood derived sample of CLL patient 09 prior to therapy
|
treatment response: partial response (PR)
wbc change: -34.1
treg fold change: -2.258333333
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 09 before thalidomide treament
|
Sample_geo_accession | GSM399728
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399728/suppl/GSM399728.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399728/suppl/GSM399728.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399729 | GPL570 |
|
CLL patient 10, untreated
|
peripheral blood derived sample of CLL patient 10 prior to therapy
|
treatment response: partial response (PR)
wbc change: 45.5
treg fold change: 1.047817048
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 10 before thalidomide treament
|
Sample_geo_accession | GSM399729
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399729/suppl/GSM399729.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399729/suppl/GSM399729.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399730 | GPL570 |
|
CLL patient 11, untreated
|
peripheral blood derived sample of CLL patient 11 prior to therapy
|
treatment response: partial response (PR)
wbc change: 28.1
treg fold change: 1.662262156
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 11 before thalidomide treament
|
Sample_geo_accession | GSM399730
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399730/suppl/GSM399730.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399730/suppl/GSM399730.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399731 | GPL570 |
|
CLL patient 12, untreated
|
peripheral blood derived sample of CLL patient 12 prior to therapy
|
treatment response: partial response (PR)
wbc change: 0.2
treg fold change: -1.916092298
flare reaction: yes
deletion 17p13: yes
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 12 before thalidomide treament
|
Sample_geo_accession | GSM399731
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399731/suppl/GSM399731.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399731/suppl/GSM399731.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399732 | GPL570 |
|
CLL patient 13, untreated
|
peripheral blood derived sample of CLL patient 13prior to therapy
|
treatment response: no response (NR)
wbc change: 45.3
treg fold change: NA
flare reaction: yes
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 13 before thalidomide treament
|
Sample_geo_accession | GSM399732
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399732/suppl/GSM399732.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399732/suppl/GSM399732.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399733 | GPL570 |
|
CLL patient 14, untreated
|
peripheral blood derived sample of CLL patient 14 prior to therapy
|
treatment response: partial response (PR)
wbc change: 29.5
treg fold change: -2.34375
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 14 before thalidomide treament
|
Sample_geo_accession | GSM399733
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399733/suppl/GSM399733.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399733/suppl/GSM399733.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399734 | GPL570 |
|
CLL patient 15, untreated
|
peripheral blood derived sample of CLL patient 15 prior to therapy
|
treatment response: no response (NR)
wbc change: 6.5
treg fold change: -2.010775862
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 15 before thalidomide treament
|
Sample_geo_accession | GSM399734
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399734/suppl/GSM399734.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399734/suppl/GSM399734.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399735 | GPL570 |
|
CLL patient 16, untreated
|
peripheral blood derived sample of CLL patient 16 prior to therapy
|
treatment response: no response (NR)
wbc change: 2.2
treg fold change: 2.021857923
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 16 before thalidomide treament
|
Sample_geo_accession | GSM399735
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399735/suppl/GSM399735.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399735/suppl/GSM399735.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399736 | GPL570 |
|
CLL patient 17, untreated
|
peripheral blood derived sample of CLL patient 17prior to therapy
|
treatment response: no response (NR)
wbc change: -3.5
treg fold change: 1.028861789
flare reaction: yes
deletion 17p13: yes
deletion 11q22-q23: no
|
Gene expression data from CLL patient 17 before thalidomide treament
|
Sample_geo_accession | GSM399736
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399736/suppl/GSM399736.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399736/suppl/GSM399736.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399737 | GPL570 |
|
CLL patient 18, untreated
|
peripheral blood derived sample of CLL patient 18 prior to therapy
|
treatment response: complete response (CR)
wbc change: 20.2
treg fold change: -2.438202247
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 18 before thalidomide treament
|
Sample_geo_accession | GSM399737
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399737/suppl/GSM399737.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399737/suppl/GSM399737.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399738 | GPL570 |
|
CLL patient 19, untreated
|
peripheral blood derived sample of CLL patient 19 prior to therapy
|
treatment response: partial response (PR)
wbc change: 10.2
treg fold change: -2.051674641
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 19 before thalidomide treament
|
Sample_geo_accession | GSM399738
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399738/suppl/GSM399738.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399738/suppl/GSM399738.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399739 | GPL570 |
|
CLL patient 20, untreated
|
peripheral blood derived sample of CLL patient 20 prior to therapy
|
treatment response: no response (NR)
wbc change: 2.9
treg fold change: -1.336082474
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 20 before thalidomide treament
|
Sample_geo_accession | GSM399739
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399739/suppl/GSM399739.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399739/suppl/GSM399739.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399740 | GPL570 |
|
CLL patient 01, thalidomide treated
|
peripheral blood derived sample of CLL patient 01 past thalidomide therapy
|
treatment response: complete response (CR)
wbc change: -5.9
treg fold change: -2.724969843
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 01 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399740
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399740/suppl/GSM399740.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399740/suppl/GSM399740.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399741 | GPL570 |
|
CLL patient 02, thalidomide treated
|
peripheral blood derived sample of CLL patient 02 past thalidomide therapy
|
treatment response: partial response (PR)
wbc change: 27.2
treg fold change: -5.151223776
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 02 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399741
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399741/suppl/GSM399741.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399741/suppl/GSM399741.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399742 | GPL570 |
|
CLL patient 03, thalidomide treated
|
peripheral blood derived sample of CLL patient 03 past thalidomide therapy
|
treatment response: complete response (CR)
wbc change: -2.7
treg fold change: -1.55654102
flare reaction: yes
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 03 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399742
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399742/suppl/GSM399742.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399742/suppl/GSM399742.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399743 | GPL570 |
|
CLL patient 04, thalidomide treated
|
peripheral blood derived sample of CLL patient 04 past thalidomide therapy
|
treatment response: no response (NR)
wbc change: -114
treg fold change: -2.881040892
flare reaction: no
deletion 17p13: yes
deletion 11q22-q23: no
|
Gene expression data from CLL patient 04 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399743
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399743/suppl/GSM399743.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399743/suppl/GSM399743.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399744 | GPL570 |
|
CLL patient 05, thalidomide treated
|
peripheral blood derived sample of CLL patient 05 past thalidomide therapy
|
treatment response: no response (NR)
wbc change: -1.1
treg fold change: NA
flare reaction: yes
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 05 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399744
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399744/suppl/GSM399744.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399744/suppl/GSM399744.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399745 | GPL570 |
|
CLL patient 06, thalidomide treated
|
peripheral blood derived sample of CLL patient 06 past thalidomide therapy
|
treatment response: no response (NR)
wbc change: 36.1
treg fold change: -19.38718663
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 06 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399745
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399745/suppl/GSM399745.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399745/suppl/GSM399745.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399746 | GPL570 |
|
CLL patient 07, thalidomide treated
|
peripheral blood derived sample of CLL patient 07 past thalidomide therapy
|
treatment response: no response (NR)
wbc change: -30
treg fold change: -1.127659574
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 07 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399746
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399746/suppl/GSM399746.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399746/suppl/GSM399746.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399747 | GPL570 |
|
CLL patient 08, thalidomide treated
|
peripheral blood derived sample of CLL patient 08 past thalidomide therapy
|
treatment response: partial response (PR)
wbc change: 12.5
treg fold change: NA
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 08 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399747
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399747/suppl/GSM399747.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399747/suppl/GSM399747.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399748 | GPL570 |
|
CLL patient 09, thalidomide treated
|
peripheral blood derived sample of CLL patient 09 past thalidomide therapy
|
treatment response: partial response (PR)
wbc change: -34.1
treg fold change: -2.258333333
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 09 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399748
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399748/suppl/GSM399748.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399748/suppl/GSM399748.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399749 | GPL570 |
|
CLL patient 10, thalidomide treated
|
peripheral blood derived sample of CLL patient 10 past thalidomide therapy
|
treatment response: partial response (PR)
wbc change: 45.5
treg fold change: 1.047817048
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 10 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399749
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399749/suppl/GSM399749.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399749/suppl/GSM399749.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399750 | GPL570 |
|
CLL patient 11, thalidomide treated
|
peripheral blood derived sample of CLL patient 11 past thalidomide therapy
|
treatment response: partial response (PR)
wbc change: 28.1
treg fold change: 1.662262156
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 11 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399750
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399750/suppl/GSM399750.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399750/suppl/GSM399750.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399751 | GPL570 |
|
CLL patient 12, thalidomide treated
|
peripheral blood derived sample of CLL patient 12 past thalidomide therapy
|
treatment response: partial response (PR)
wbc change: 0.2
treg fold change: -1.916092298
flare reaction: yes
deletion 17p13: yes
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 12 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399751
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399751/suppl/GSM399751.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399751/suppl/GSM399751.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399752 | GPL570 |
|
CLL patient 13, thalidomide treated
|
peripheral blood derived sample of CLL patient 13past thalidomide therapy
|
treatment response: no response (NR)
wbc change: 45.3
treg fold change: NA
flare reaction: yes
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 13 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399752
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399752/suppl/GSM399752.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399752/suppl/GSM399752.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399753 | GPL570 |
|
CLL patient 14, thalidomide treated
|
peripheral blood derived sample of CLL patient 14 past thalidomide therapy
|
treatment response: partial response (PR)
wbc change: 29.5
treg fold change: -2.34375
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 14 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399753
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399753/suppl/GSM399753.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399753/suppl/GSM399753.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399754 | GPL570 |
|
CLL patient 15, thalidomide treated
|
peripheral blood derived sample of CLL patient 15 past thalidomide therapy
|
treatment response: no response (NR)
wbc change: 6.5
treg fold change: -2.010775862
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 15 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399754
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399754/suppl/GSM399754.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399754/suppl/GSM399754.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399755 | GPL570 |
|
CLL patient 16, thalidomide treated
|
peripheral blood derived sample of CLL patient 16 past thalidomide therapy
|
treatment response: no response (NR)
wbc change: 2.2
treg fold change: 2.021857923
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 16 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399755
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399755/suppl/GSM399755.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399755/suppl/GSM399755.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399756 | GPL570 |
|
CLL patient 17, thalidomide treated
|
peripheral blood derived sample of CLL patient 17past thalidomide therapy
|
treatment response: no response (NR)
wbc change: -3.5
treg fold change: 1.028861789
flare reaction: yes
deletion 17p13: yes
deletion 11q22-q23: no
|
Gene expression data from CLL patient 17 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399756
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399756/suppl/GSM399756.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399756/suppl/GSM399756.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399757 | GPL570 |
|
CLL patient 18, thalidomide treated
|
peripheral blood derived sample of CLL patient 18 past thalidomide therapy
|
treatment response: complete response (CR)
wbc change: 20.2
treg fold change: -2.438202247
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: no
|
Gene expression data from CLL patient 18 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399757
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399757/suppl/GSM399757.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399757/suppl/GSM399757.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399758 | GPL570 |
|
CLL patient 19, thalidomide treated
|
peripheral blood derived sample of CLL patient 19 past thalidomide therapy
|
treatment response: partial response (PR)
wbc change: 10.2
treg fold change: -2.051674641
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 19 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399758
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399758/suppl/GSM399758.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399758/suppl/GSM399758.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
GSM399759 | GPL570 |
|
CLL patient 20, thalidomide treated
|
peripheral blood derived sample of CLL patient 20 past thalidomide therapy
|
treatment response: no response (NR)
wbc change: 2.9
treg fold change: -1.336082474
flare reaction: no
deletion 17p13: no
deletion 11q22-q23: yes
|
Gene expression data from CLL patient 20 following 7 days of thalidomide treament
|
Sample_geo_accession | GSM399759
| Sample_status | Public on Aug 21 2009
| Sample_submission_date | May 02 2009
| Sample_last_update_date | Aug 21 2009
| Sample_type | RNA
| Sample_channel_count | 1
| Sample_organism_ch1 | Homo sapiens
| Sample_taxid_ch1 | 9606
| Sample_treatment_protocol_ch1 | CLL patients received thalidomide (100mg p.o./day) for 7 days
| Sample_molecule_ch1 | total RNA
| Sample_extract_protocol_ch1 | RNA was isolated from peripheral blood samples enriched for leukemic cells by Ficoll-density gradient centrifugation (percentage of leukemic cells > 90%) using Trizol according to the manufacturer’s recommendations
| Sample_label_ch1 | biotin
| Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 1 ug total RNA using the GeneChip One-Cycle cDNA Synthesis Kit (Affymetrix; manufacturer’s recommendations)
| Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip U133plus2.0 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 450.
| Sample_scan_protocol | GeneChips were scanned using a GeneChip® Scanner 3000 7G
| Sample_data_processing | The data were analyzed with the GCOS software and BRB Array Tools
| Sample_platform_id | GPL570
| Sample_contact_name | Lars,,Bullinger
| Sample_contact_email | lars.bullinger@uniklinik-ulm.de
| Sample_contact_phone | +49-731-500-45501
| Sample_contact_fax | +49-731-500-45505
| Sample_contact_department | Internal Medicine III
| Sample_contact_institute | University of Ulm
| Sample_contact_address | Albert-Einstein-Allee 23
| Sample_contact_city | Ulm
| Sample_contact_zip/postal_code | 89081
| Sample_contact_country | Germany
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399759/suppl/GSM399759.CEL.gz
| Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM399nnn/GSM399759/suppl/GSM399759.CHP.gz
| Sample_series_id | GSE15913
| Sample_data_row_count | 54675
| |
|
|
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Select GSMs and click on "Add groups" |
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