Search results for the GEO ID: GSE2376
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Title
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Description
Characteristics
GSM44820
GPL339
+/+ no.2 CD4 cells from wildtype mouse Male C57BL/6 mice were treated with ENU to generate single base substitutions, the variant genome sequences were breed to homozygosity in inbreeding pedigrees, and screened for antinuclear autoantibodies (ANA). The sanroque pedigree contained multiple progeny with ANA of mixed homogeneous nuclear and cytoplasmic immunofluorescence pattern by 12 weeks of age, due to an autosomal recessive gene variant. Comparsion of the gene expression profile of CD4 cells from Sanroque to wild type was performed.
GSM44825
GPL339
san/san pt 2 CD4 cells from Sanroque Male C57BL/6 mice were treated with ENU to generate single base substitutions, the variant genome sequences were breed to homozygosity in inbreeding pedigrees, and screened for antinuclear autoantibodies (ANA). The sanroque pedigree contained multiple progeny with ANA of mixed homogeneous nuclear and cytoplasmic immunofluorescence pattern by 12 weeks of age, due to an autosomal recessive gene variant. Comparsion of the gene expression profile of CD4 cells from sanroque to wildtype was performed.
GSM44828
GPL339
+/+ pt 1 CD4 cells from wildtype Male C57BL/6 mice were treated with ENU to generate single base substitutions, the variant genome sequences were breed to homozygosity in inbreeding pedigrees, and screened for antinuclear autoantibodies (ANA). The sanroque pedigree contained multiple progeny with ANA of mixed homogeneous nuclear and cytoplasmic immunofluorescence pattern by 12 weeks of age, due to an autosomal recessive gene variant. Comparsion of the gene expression profile of CD4 cells from sanroque to wildtype was performed.
GSM44831
GPL339
san/san no.1 CD4 cells from sanroque Male C57BL/6 mice were treated with ENU to generate single base substitutions, the variant genome sequences were breed to homozygosity in inbreeding pedigrees, and screened for antinuclear autoantibodies (ANA). The sanroque pedigree contained multiple progeny with ANA of mixed homogeneous nuclear and cytoplasmic immunofluorescence pattern by 12 weeks of age, due to an autosomal recessive gene variant. Comparsion of the gene expression profile of CD4 cells from sanroque to wildtype was performed.
 
 
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