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Search results for the GEO ID: GSE2535
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GSM48354
GPL8300
Patient 67 Leipzig Non-Responder Peripheral Blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48355
GPL8300
Patient 70 Leipzig Non-Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48356
GPL8300
Patient 316 Leipzig Non-Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48357
GPL8300
Patient 1258 Leipzig Non-Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48358
GPL8300
Patient 1290 Leipzig Non-Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48359
GPL8300
Patient 40 Leipzig Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48360
GPL8300
Patient 96 Leipzig Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48361
GPL8300
Patient 481 Leipzig Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48362
GPL8300
Patient 518 Leipzig Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48363
GPL8300
Patient 695 Leipzig Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48364
GPL8300
Patient 988 Leipzig Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48365
GPL8300
Patient 998 Leipzig Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48366
GPL8300
Patient 1169 Leipzig Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the training set from Leipzig. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48367
GPL8300
Patient 1 Mannheim Non-Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48368
GPL8300
Patient 1844 Mannheim NonResponder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48369
GPL8300
Patient 1866 Mannheim Non-Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48370
GPL8300
Patient 2028 Mannheim Non-Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48371
GPL8300
Patient 2115 Mannheim Non-Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48372
GPL8300
Patient 2210 Mannheim Non-Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48373
GPL8300
Patient 92239 Mannheim Non-Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a non-responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48374
GPL8300
Patient 2023 Mannhiem Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48375
GPL8300
Patient 1035D Mannhiem Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48376
GPL8300
Patient 11008 Mannhiem Responder Peripheral blood or bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48377
GPL8300
Patient 1229 Mannhiem Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48378
GPL8300
Patient 1399 Mannhiem Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48379
GPL8300
Patient 201 Mannhiem Responder Bone marrow from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48380
GPL8300
Patient 2025 Mannhiem Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = Gleevec Keywords = cytogenetic responses Keywords = Affymetrix
GSM48381
GPL8300
Patient 962 Mannhiem Responder Peripheral blood from patients with chronic myelogenous leukemia before treatment with imatinib The sample is a responder to imatinib treatment and belongs in the validation set from Mannheim. The sample originated from blood or bone marrow from patient with chronic myelogenous leukemia (CML), before imatinib treatment. Red blood cells were removed by red cell lysis buffer. Either guanidine-thiocyanate / phenol-cholorform extraction followed by RNeasy (Leipzig), or cesium chloride-gradient purification (Mannheim) were used to extract total RNA from the patient’s white blood cells. Labeling and hybridization is done by standard Affymetrix protocols. Scanning is done by HP GeneArray Scanner and image analysis is carried out by Affymetrix Microarray Suite Software, version 5.0. Robust Multipchip Analysis (RMA) was used for signal quantification, on Bioconductor (http://www.bioconductor.org). Keywords = chronic myelogenous leukemia Keywords = imatinib Keywords = cytogenetic responses Keywords = Gleevec Keywords = Affymetrix
 
 
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