Search results for the GEO ID: GSE39525  |
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|
GSM ID | GPL ID |
Select for analysis |
Title |
Source name |
Description |
Characteristics |
GSM970876 | GPL1355 |
|
vehicle-liver-rat1
|
vehicle
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 day orally with 0.2% HPMC at 10 ml/kg/day
|
| Sample_geo_accession | GSM970876
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970876/suppl/GSM970876_CMet07-043-046-050_h2.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970877 | GPL1355 |
|
vehicle-liver-rat2
|
vehicle
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 day orally with 0.2% HPMC at 10 ml/kg/day
|
| Sample_geo_accession | GSM970877
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970877/suppl/GSM970877_CMet07-043-046-050_a3.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970878 | GPL1355 |
|
vehicle-liver-rat3
|
vehicle
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 day orally with 0.2% HPMC at 10 ml/kg/day
|
| Sample_geo_accession | GSM970878
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970878/suppl/GSM970878_CMet07-043-046-050_b3.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970879 | GPL1355 |
|
30mg/kg-liver-rat1
|
30mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 30 mg/kg/day
|
| Sample_geo_accession | GSM970879
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970879/suppl/GSM970879_CMet07-043-046-050_c3.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970880 | GPL1355 |
|
30mg/kg-liver-rat2
|
30mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 30 mg/kg/day
|
| Sample_geo_accession | GSM970880
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970880/suppl/GSM970880_CMet07-043-046-050_d3.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970881 | GPL1355 |
|
30mg/kg-liver-rat3
|
30mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 30 mg/kg/day
|
| Sample_geo_accession | GSM970881
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970881/suppl/GSM970881_CMet07-043-046-050_e3.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970882 | GPL1355 |
|
100mg/kg-liver-rat1
|
100mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 100 mg/kg/day
|
| Sample_geo_accession | GSM970882
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970882/suppl/GSM970882_CMet07-043-046-050_f3.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970883 | GPL1355 |
|
100mg/kg-liver-rat2
|
100mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 100 mg/kg/day
|
| Sample_geo_accession | GSM970883
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970883/suppl/GSM970883_CMet07-043-046-050_g3.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970884 | GPL1355 |
|
100mg/kg-liver-rat3
|
100mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 100 mg/kg/day
|
| Sample_geo_accession | GSM970884
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970884/suppl/GSM970884_CMet07-043-046-050_h3.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970885 | GPL1355 |
|
200mg/kg-liver-rat1
|
200mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 300 mg/kg/day
|
| Sample_geo_accession | GSM970885
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970885/suppl/GSM970885_CMet07-043-046-050_a4.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970886 | GPL1355 |
|
200mg/kg-liver-rat2
|
200mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 300 mg/kg/day
|
| Sample_geo_accession | GSM970886
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970886/suppl/GSM970886_CMet07-043-046-050_b4.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
|
GSM970887 | GPL1355 |
|
200mg/kg-liver-rat3
|
200mg/kg A-998679
|
strain: Sprague Dawley
gender: male
weight: 176-200g
tissue: liver
|
Gene expression data from liver of rats treated for 5 days orally with A-998679 at 300 mg/kg/day
|
| Sample_geo_accession | GSM970887
| | Sample_status | Public on Jul 24 2012
| | Sample_submission_date | Jul 20 2012
| | Sample_last_update_date | Aug 03 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Rattus norvegicus
| | Sample_taxid_ch1 | 10116
| | Sample_treatment_protocol_ch1 | livers from vehicle and compound treated rats were flash frozen in LN2 at necropsy
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Trizol extraction of total RNA was performed according to the manufacturer's instructions.
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA were prepared according to the standard Affymetrix protocol from 5 ug total RNA (Expression Analysis Technical Manual, 2001, Affymetrix).
| | Sample_hyb_protocol | Following fragmentation, 15 ug of cRNA were hybridized for 16 hr at 45C on GeneChip Rat 230_2 Genome Array. GeneChips were washed and stained in the Affymetrix Fluidics Station 400.
| | Sample_scan_protocol | GeneChips were scanned using the Hewlett-Packard GeneArray Scanner G3000.
| | Sample_data_processing = Log intensity and p values generated in Rosetta Resolver (version 7.2) based on imported Affymetrix .cel files with mean scaling (controls and flagged spots excluded, trim percentage of '10.0') and standard (untransformed) detrending algorithm for non-linearity correction (max bins = '40'; trim percentage | '20.0'). Fold change; all gene expression changes with fold change at least +/-1.5 and p<0.05 in at least one sample; changes not meeting these parameters are considered unchanged (FC=1).
| | Sample_platform_id | GPL1355
| | Sample_contact_name | Rita,,Ciurlionis
| | Sample_contact_email | rita.ciurlionis@abbott.com
| | Sample_contact_phone | (847)935-6258
| | Sample_contact_institute | Abbott Laboratories
| | Sample_contact_address | 100 Abbott Park Rd
| | Sample_contact_city | Abbott Park
| | Sample_contact_state | IL
| | Sample_contact_zip/postal_code | 60064
| | Sample_contact_country | USA
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM970nnn/GSM970887/suppl/GSM970887_CMet07-043-046-050_c4.CEL.gz
| | Sample_series_id | GSE39525
| | Sample_series_id | GSE39875
| | Sample_data_row_count | 29176
| | |
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