Search results for the GEO ID: GSE42813  |
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|
GSM ID | GPL ID |
Select for analysis |
Title |
Source name |
Description |
Characteristics |
GSM478606 | GPL1261 |
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Aorta_APOE-deficient with atherosclerosis_1
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Aortas isolated from atherosclerotic APOE-deficient mice
|
strain: C57BL/6J
genotype: APOE-deficient
tissue: aorta
treatment: none
disease: atherosclerosis
age: 32-34 weeks
|
Gene expression data from atherosclerotic aortas isolated from APOE-deficient mice.
APOE-1
|
| Sample_geo_accession | GSM478606
| | Sample_status | Public on Dec 03 2009
| | Sample_submission_date | Dec 02 2009
| | Sample_last_update_date | Dec 02 2009
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Mus musculus
| | Sample_taxid_ch1 | 10090
| | Sample_treatment_protocol_ch1 | The study was performed with aortas isolated from three groups of mice (32-34 weeks of age), i.e. untreated APOE-deficient mice (APOE), APOE-deficient mice treated with captopril (20 mg/kg in drinking water) for 7 months (Capto), and nontransgenic control mice (Cont).
| | Sample_growth_protocol_ch1 | The study was initiated with 4-6 week-old APOE-deficient mice on a C57BL/6J background, and non-transgenic C57BL/6J controls. Mice had free access to food and water, and were fed a standard rodent chow containing 7 % fat and 0.15 % cholesterol (Ain 93-based diet). For atherosclerosis treatment, one subgroup of APOE-deficient mice received captopril in drinking water (20 mg/kg) for 7 months. At an age of 32-34 weeks, aortas were isolated from three study groups (APOE-deficient, captopril-treated APOE-deficient, and nontransgenic control mice), dissected free of fat, and immediately frozen in liquid nitrogen.
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total aortic RNA was isolated with the RNeasy Midi kit according to the manufacturer`s instructions (Qiagen).
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA was prepared according to the protocol of the manufacturer (Affymetrix; GeneChip Expression Analysis Technical Manual; Rev. 5).
| | Sample_hyb_protocol | For hybridization, 15 µg of fragmented cRNA were incubated with the chip (Mouse Genome MG430 2.0 Array) in 200 µl of the hybridization solution in a Hybridization Oven 640 (Affymetrix) for 16 h at 45 °C. GeneChips were then washed and stained using the Affymetrix Fluidics Station 450 according to the GeneChip Expression Analysis Technical Manual (Rev. 5).
| | Sample_scan_protocol | GeneChips were scanned using the Affymetrix GeneChip Scanner 7G.
| | Sample_data_processing | The signals were processed using Affymetrix GeneChip Operating Software (GCOS; v.1.4; Affymetrix). To compare samples and experiments, the trimmed mean signal of each array was scaled to a target intensity of 200.
| | Sample_platform_id | GPL1261
| | Sample_contact_name | Ursula,,Quitterer
| | Sample_contact_email | ursula.quitterer@pharma.ethz.ch
| | Sample_contact_phone | 0041 44 635 6001
| | Sample_contact_fax | 0041 44 635 6881
| | Sample_contact_department | Molecular Pharmacology
| | Sample_contact_institute | Swiss Federal Institute of Technology
| | Sample_contact_address | Winterthurerstrasse 190
| | Sample_contact_city | Zurich
| | Sample_contact_zip/postal_code | CH-8057
| | Sample_contact_country | Switzerland
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM478nnn/GSM478606/suppl/GSM478606.CEL.gz
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM478nnn/GSM478606/suppl/GSM478606.CHP.gz
| | Sample_series_id | GSE19286
| | Sample_series_id | GSE42813
| | Sample_data_row_count | 45101
| | |
|
GSM478607 | GPL1261 |
|
Aorta_APOE-deficient with atherosclerosis_2
|
Aortas isolated from atherosclerotic APOE-deficient mice
|
strain: C57BL/6J
genotype: APOE-deficient
tissue: aorta
treatment: none
disease: atherosclerosis
age: 32-34 weeks
|
Gene expression data from atherosclerotic aortas isolated from APOE-deficient mice.
APOE-2
|
| Sample_geo_accession | GSM478607
| | Sample_status | Public on Dec 03 2009
| | Sample_submission_date | Dec 02 2009
| | Sample_last_update_date | Dec 02 2009
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Mus musculus
| | Sample_taxid_ch1 | 10090
| | Sample_treatment_protocol_ch1 | The study was performed with aortas isolated from three groups of mice (32-34 weeks of age), i.e. untreated APOE-deficient mice (APOE), APOE-deficient mice treated with captopril (20 mg/kg in drinking water) for 7 months (Capto), and nontransgenic control mice (Cont).
| | Sample_growth_protocol_ch1 | The study was initiated with 4-6 week-old APOE-deficient mice on a C57BL/6J background, and non-transgenic C57BL/6J controls. Mice had free access to food and water, and were fed a standard rodent chow containing 7 % fat and 0.15 % cholesterol (Ain 93-based diet). For atherosclerosis treatment, one subgroup of APOE-deficient mice received captopril in drinking water (20 mg/kg) for 7 months. At an age of 32-34 weeks, aortas were isolated from three study groups (APOE-deficient, captopril-treated APOE-deficient, and nontransgenic control mice), dissected free of fat, and immediately frozen in liquid nitrogen.
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total aortic RNA was isolated with the RNeasy Midi kit according to the manufacturer`s instructions (Qiagen).
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA was prepared according to the protocol of the manufacturer (Affymetrix; GeneChip Expression Analysis Technical Manual; Rev. 5).
| | Sample_hyb_protocol | For hybridization, 15 µg of fragmented cRNA were incubated with the chip (Mouse Genome MG430 2.0 Array) in 200 µl of the hybridization solution in a Hybridization Oven 640 (Affymetrix) for 16 h at 45 °C. GeneChips were then washed and stained using the Affymetrix Fluidics Station 450 according to the GeneChip Expression Analysis Technical Manual (Rev. 5).
| | Sample_scan_protocol | GeneChips were scanned using the Affymetrix GeneChip Scanner 7G.
| | Sample_data_processing | The signals were processed using Affymetrix GeneChip Operating Software (GCOS; v.1.4; Affymetrix). To compare samples and experiments, the trimmed mean signal of each array was scaled to a target intensity of 200.
| | Sample_platform_id | GPL1261
| | Sample_contact_name | Ursula,,Quitterer
| | Sample_contact_email | ursula.quitterer@pharma.ethz.ch
| | Sample_contact_phone | 0041 44 635 6001
| | Sample_contact_fax | 0041 44 635 6881
| | Sample_contact_department | Molecular Pharmacology
| | Sample_contact_institute | Swiss Federal Institute of Technology
| | Sample_contact_address | Winterthurerstrasse 190
| | Sample_contact_city | Zurich
| | Sample_contact_zip/postal_code | CH-8057
| | Sample_contact_country | Switzerland
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM478nnn/GSM478607/suppl/GSM478607.CEL.gz
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM478nnn/GSM478607/suppl/GSM478607.CHP.gz
| | Sample_series_id | GSE19286
| | Sample_series_id | GSE42813
| | Sample_data_row_count | 45101
| | |
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GSM478610 | GPL1261 |
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Aorta_non-transgenic C57BL/6J control_1
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Aortas isolated from non-transgenic C57BL/6J control mice
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strain: C57BL/6J
genotype: non-transgenic
tissue: aorta
age: 32-34 weeks
|
Gene expression data from aortas isolated from non-transgenic C57BL/6J control mice.
Cont-1
|
| Sample_geo_accession | GSM478610
| | Sample_status | Public on Dec 03 2009
| | Sample_submission_date | Dec 02 2009
| | Sample_last_update_date | Dec 02 2009
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Mus musculus
| | Sample_taxid_ch1 | 10090
| | Sample_treatment_protocol_ch1 | The study was performed with aortas isolated from three groups of mice (32-34 weeks of age), i.e. untreated APOE-deficient mice (APOE), APOE-deficient mice treated with captopril (20 mg/kg in drinking water) for 7 months (Capto), and nontransgenic control mice (Cont).
| | Sample_growth_protocol_ch1 | The study was initiated with 4-6 week-old APOE-deficient mice on a C57BL/6J background, and non-transgenic C57BL/6J controls. Mice had free access to food and water, and were fed a standard rodent chow containing 7 % fat and 0.15 % cholesterol (Ain 93-based diet). For atherosclerosis treatment, one subgroup of APOE-deficient mice received captopril in drinking water (20 mg/kg) for 7 months. At an age of 32-34 weeks, aortas were isolated from three study groups (APOE-deficient, captopril-treated APOE-deficient, and nontransgenic control mice), dissected free of fat, and immediately frozen in liquid nitrogen.
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total aortic RNA was isolated with the RNeasy Midi kit according to the manufacturer`s instructions (Qiagen).
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA was prepared according to the protocol of the manufacturer (Affymetrix; GeneChip Expression Analysis Technical Manual; Rev. 5).
| | Sample_hyb_protocol | For hybridization, 15 µg of fragmented cRNA were incubated with the chip (Mouse Genome MG430 2.0 Array) in 200 µl of the hybridization solution in a Hybridization Oven 640 (Affymetrix) for 16 h at 45 °C. GeneChips were then washed and stained using the Affymetrix Fluidics Station 450 according to the GeneChip Expression Analysis Technical Manual (Rev. 5).
| | Sample_scan_protocol | GeneChips were scanned using the Affymetrix GeneChip Scanner 7G.
| | Sample_data_processing | The signals were processed using Affymetrix GeneChip Operating Software (GCOS; v.1.4; Affymetrix). To compare samples and experiments, the trimmed mean signal of each array was scaled to a target intensity of 200.
| | Sample_platform_id | GPL1261
| | Sample_contact_name | Ursula,,Quitterer
| | Sample_contact_email | ursula.quitterer@pharma.ethz.ch
| | Sample_contact_phone | 0041 44 635 6001
| | Sample_contact_fax | 0041 44 635 6881
| | Sample_contact_department | Molecular Pharmacology
| | Sample_contact_institute | Swiss Federal Institute of Technology
| | Sample_contact_address | Winterthurerstrasse 190
| | Sample_contact_city | Zurich
| | Sample_contact_zip/postal_code | CH-8057
| | Sample_contact_country | Switzerland
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM478nnn/GSM478610/suppl/GSM478610.CEL.gz
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM478nnn/GSM478610/suppl/GSM478610.CHP.gz
| | Sample_series_id | GSE19286
| | Sample_series_id | GSE42813
| | Sample_data_row_count | 45101
| | |
|
GSM478611 | GPL1261 |
|
Aorta_non-transgenic C57BL/6J control_2
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Aortas isolated from non-transgenic C57BL/6J control mice
|
strain: C57BL/6J
genotype: non-transgenic
tissue: aorta
age: 32-34 weeks
|
Gene expression data from aortas isolated from non-transgenic C57BL/6J control mice.
Cont-2
|
| Sample_geo_accession | GSM478611
| | Sample_status | Public on Dec 03 2009
| | Sample_submission_date | Dec 02 2009
| | Sample_last_update_date | Dec 02 2009
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Mus musculus
| | Sample_taxid_ch1 | 10090
| | Sample_treatment_protocol_ch1 | The study was performed with aortas isolated from three groups of mice (32-34 weeks of age), i.e. untreated APOE-deficient mice (APOE), APOE-deficient mice treated with captopril (20 mg/kg in drinking water) for 7 months (Capto), and nontransgenic control mice (Cont).
| | Sample_growth_protocol_ch1 | The study was initiated with 4-6 week-old APOE-deficient mice on a C57BL/6J background, and non-transgenic C57BL/6J controls. Mice had free access to food and water, and were fed a standard rodent chow containing 7 % fat and 0.15 % cholesterol (Ain 93-based diet). For atherosclerosis treatment, one subgroup of APOE-deficient mice received captopril in drinking water (20 mg/kg) for 7 months. At an age of 32-34 weeks, aortas were isolated from three study groups (APOE-deficient, captopril-treated APOE-deficient, and nontransgenic control mice), dissected free of fat, and immediately frozen in liquid nitrogen.
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total aortic RNA was isolated with the RNeasy Midi kit according to the manufacturer`s instructions (Qiagen).
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA was prepared according to the protocol of the manufacturer (Affymetrix; GeneChip Expression Analysis Technical Manual; Rev. 5).
| | Sample_hyb_protocol | For hybridization, 15 µg of fragmented cRNA were incubated with the chip (Mouse Genome MG430 2.0 Array) in 200 µl of the hybridization solution in a Hybridization Oven 640 (Affymetrix) for 16 h at 45 °C. GeneChips were then washed and stained using the Affymetrix Fluidics Station 450 according to the GeneChip Expression Analysis Technical Manual (Rev. 5).
| | Sample_scan_protocol | GeneChips were scanned using the Affymetrix GeneChip Scanner 7G.
| | Sample_data_processing | The signals were processed using Affymetrix GeneChip Operating Software (GCOS; v.1.4; Affymetrix). To compare samples and experiments, the trimmed mean signal of each array was scaled to a target intensity of 200.
| | Sample_platform_id | GPL1261
| | Sample_contact_name | Ursula,,Quitterer
| | Sample_contact_email | ursula.quitterer@pharma.ethz.ch
| | Sample_contact_phone | 0041 44 635 6001
| | Sample_contact_fax | 0041 44 635 6881
| | Sample_contact_department | Molecular Pharmacology
| | Sample_contact_institute | Swiss Federal Institute of Technology
| | Sample_contact_address | Winterthurerstrasse 190
| | Sample_contact_city | Zurich
| | Sample_contact_zip/postal_code | CH-8057
| | Sample_contact_country | Switzerland
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM478nnn/GSM478611/suppl/GSM478611.CEL.gz
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM478nnn/GSM478611/suppl/GSM478611.CHP.gz
| | Sample_series_id | GSE19286
| | Sample_series_id | GSE42813
| | Sample_data_row_count | 45101
| | |
|
GSM1050380 | GPL1261 |
|
Aorta-APOE-deficient and vitamin E treatment-rep1
|
Aortas isolated from vitamin E-treated APOE-deficient mice
|
tissue: aorta
genetic background: C57BL/6J
genotype: APOE-deficient
treatment: vitamin E
sample type: aortas from vitamin E-treated APOE-deficient mice
|
Gene expression data of aortas isolated from vitamin E-treated APOE-deficient mice
|
| Sample_geo_accession | GSM1050380
| | Sample_status | Public on Dec 11 2012
| | Sample_submission_date | Dec 10 2012
| | Sample_last_update_date | Dec 11 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Mus musculus
| | Sample_taxid_ch1 | 10090
| | Sample_treatment_protocol_ch1 | The study was performed with aortas isolated from three groups of mice (32-34 weeks of age), i.e. untreated APOE-deficient mice (APOE), APOE-deficient mice treated with vitamin E (2000 IU/kg diet) for 7 months (VitE), and B6 control mice (Cont).
| | Sample_growth_protocol_ch1 | The study was initiated with 4-6 week-old APOE-deficient mice on a B6 (C57BL/6J) background, and non-transgenic B6 controls. Mice had free access to food and water, and were fed a standard rodent chow containing 7 % fat and 0.15 % cholesterol (Ain 93-based diet). For atherosclerosis treatment, a group of APOE-deficient mice received treatment with the antioxidant vitamin E (2000 IU/kg diet) for 7 months. At an age of 32-34 weeks, aortas were isolated from three study groups (APOE-deficient, vitamin E-treated APOE-deficient, and nontransgenic B6 control mice), dissected free of fat, and immediately frozen in liquid nitrogen.
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total aortic RNA was isolated with the RNeasy Midi kit according to the manufacturer`s instructions (Qiagen).
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA was prepared according to the protocol of the manufacturer (Affymetrix; GeneChip Expression Analysis Technical Manual).
| | Sample_hyb_protocol | For hybridization, 15 µg of fragmented cRNA were incubated with the chip (Mouse Genome MG430 2.0 Array) in 200 µl of the hybrization solution in a Hybridization Oven 640 (Affymetrix) for 16 h at 45 °C. GeneChips were then washed and stained using the Affymetrix Fluidics Station 450 according to the GeneChip Expression Analysis Technical Manual.
| | Sample_scan_protocol | GeneChips were scanned using the Affymetrix GeneChip Scanner 7G.
| | Sample_data_processing | The signals were processed using Affymetrix GeneChip Operating Software (GCOS; v.1.4; Affymetrix). To compare samples and experiments, the trimmed mean signal of each array was scaled to a target intensity of 200.
| | Sample_platform_id | GPL1261
| | Sample_contact_name | Ursula,,Quitterer
| | Sample_contact_email | ursula.quitterer@pharma.ethz.ch
| | Sample_contact_phone | 0041 44 635 6001
| | Sample_contact_fax | 0041 44 635 6881
| | Sample_contact_department | Molecular Pharmacology
| | Sample_contact_institute | Swiss Federal Institute of Technology
| | Sample_contact_address | Winterthurerstrasse 190
| | Sample_contact_city | Zurich
| | Sample_contact_zip/postal_code | CH-8057
| | Sample_contact_country | Switzerland
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM1050nnn/GSM1050380/suppl/GSM1050380_VitE-1.CEL.gz
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM1050nnn/GSM1050380/suppl/GSM1050380_VitE-1.CHP.gz
| | Sample_series_id | GSE42813
| | Sample_data_row_count | 45101
| | |
|
GSM1050381 | GPL1261 |
|
Aorta-APOE-deficient and vitamin E treatment-rep2
|
Aortas isolated from vitamin E-treated APOE-deficient mice
|
tissue: aorta
genetic background: C57BL/6J
genotype: APOE-deficient
treatment: vitamin E
sample type: aortas from vitamin E-treated APOE-deficient mice
|
Gene expression data of aortas isolated from vitamin E-treated APOE-deficient mice
|
| Sample_geo_accession | GSM1050381
| | Sample_status | Public on Dec 11 2012
| | Sample_submission_date | Dec 10 2012
| | Sample_last_update_date | Dec 11 2012
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Mus musculus
| | Sample_taxid_ch1 | 10090
| | Sample_treatment_protocol_ch1 | The study was performed with aortas isolated from three groups of mice (32-34 weeks of age), i.e. untreated APOE-deficient mice (APOE), APOE-deficient mice treated with vitamin E (2000 IU/kg diet) for 7 months (VitE), and B6 control mice (Cont).
| | Sample_growth_protocol_ch1 | The study was initiated with 4-6 week-old APOE-deficient mice on a B6 (C57BL/6J) background, and non-transgenic B6 controls. Mice had free access to food and water, and were fed a standard rodent chow containing 7 % fat and 0.15 % cholesterol (Ain 93-based diet). For atherosclerosis treatment, a group of APOE-deficient mice received treatment with the antioxidant vitamin E (2000 IU/kg diet) for 7 months. At an age of 32-34 weeks, aortas were isolated from three study groups (APOE-deficient, vitamin E-treated APOE-deficient, and nontransgenic B6 control mice), dissected free of fat, and immediately frozen in liquid nitrogen.
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total aortic RNA was isolated with the RNeasy Midi kit according to the manufacturer`s instructions (Qiagen).
| | Sample_label_ch1 | biotin
| | Sample_label_protocol_ch1 | Biotinylated cRNA was prepared according to the protocol of the manufacturer (Affymetrix; GeneChip Expression Analysis Technical Manual).
| | Sample_hyb_protocol | For hybridization, 15 µg of fragmented cRNA were incubated with the chip (Mouse Genome MG430 2.0 Array) in 200 µl of the hybrization solution in a Hybridization Oven 640 (Affymetrix) for 16 h at 45 °C. GeneChips were then washed and stained using the Affymetrix Fluidics Station 450 according to the GeneChip Expression Analysis Technical Manual.
| | Sample_scan_protocol | GeneChips were scanned using the Affymetrix GeneChip Scanner 7G.
| | Sample_data_processing | The signals were processed using Affymetrix GeneChip Operating Software (GCOS; v.1.4; Affymetrix). To compare samples and experiments, the trimmed mean signal of each array was scaled to a target intensity of 200.
| | Sample_platform_id | GPL1261
| | Sample_contact_name | Ursula,,Quitterer
| | Sample_contact_email | ursula.quitterer@pharma.ethz.ch
| | Sample_contact_phone | 0041 44 635 6001
| | Sample_contact_fax | 0041 44 635 6881
| | Sample_contact_department | Molecular Pharmacology
| | Sample_contact_institute | Swiss Federal Institute of Technology
| | Sample_contact_address | Winterthurerstrasse 190
| | Sample_contact_city | Zurich
| | Sample_contact_zip/postal_code | CH-8057
| | Sample_contact_country | Switzerland
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM1050nnn/GSM1050381/suppl/GSM1050381_VitE-2.CEL.gz
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM1050nnn/GSM1050381/suppl/GSM1050381_VitE-2.CHP.gz
| | Sample_series_id | GSE42813
| | Sample_data_row_count | 45101
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