Search results for the GEO ID: GSE5389  |
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|
GSM ID | GPL ID |
Select for analysis |
Title |
Source name |
Description |
Characteristics |
GSM123243 | GPL96 |
|
brain_OFC_bipolar B_mr212
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 31
Gender: Male
Age of onset (years): 21
Duration of illness (years): 10
Brain pH: 6.3
Post mortem interval (hours): 28
Side of brain: Right
Fluphenazine mg. Equivalents: 30000
Lithium treatment: No
Valproate treatment: No
Electroconvulsive therapy: No
Suicide: Yes
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 5
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 6
|
none
|
| Sample_geo_accession | GSM123243
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123243/suppl/GSM123243.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123244 | GPL96 |
|
brain_OFC_bipolar B_mr221
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 50
Gender: Female
Age of onset (years): 25
Duration of illness (years): 25
Brain pH: 6.3
Post mortem interval (hours): 62
Side of brain: Left
Fluphenazine mg. Equivalents: 0
Lithium treatment: No
Valproate treatment: Yes
Electroconvulsive therapy: No
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 0
|
none
|
| Sample_geo_accession | GSM123244
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123244/suppl/GSM123244.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123245 | GPL96 |
|
brain_OFC_bipolar B_mr233
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 50
Gender: Male
Age of onset (years): 17
Duration of illness (years): 23
Brain pH: 6.2
Post mortem interval (hours): 19
Side of brain: Left
Fluphenazine mg. Equivalents: 60000
Lithium treatment: No
Valproate treatment: Yes
Electroconvulsive therapy: No
Suicide: Yes
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 1
|
none
|
| Sample_geo_accession | GSM123245
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123245/suppl/GSM123245.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123246 | GPL96 |
|
brain_OFC_bipolar B_mr351
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 48
Gender: Female
Age of onset (years): 16
Duration of illness (years): 32
Brain pH: 5.8
Post mortem interval (hours): 22
Side of brain: Left
Fluphenazine mg. Equivalents: 32000
Lithium treatment: No
Valproate treatment: Yes
Electroconvulsive therapy: No
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 3
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 5
|
none
|
| Sample_geo_accession | GSM123246
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123246/suppl/GSM123246.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123247 | GPL96 |
|
brain_OFC_bipolar B_mr384
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 61
Gender: Female
Age of onset (years): 18
Duration of illness (years): 43
Brain pH: 6.5
Post mortem interval (hours): 60
Side of brain: Left
Fluphenazine mg. Equivalents: 40000
Lithium treatment: Yes
Valproate treatment: No
Electroconvulsive therapy: Yes (5 treatments)
Suicide: Yes
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 1
|
none
|
| Sample_geo_accession | GSM123247
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123247/suppl/GSM123247.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123248 | GPL96 |
|
brain_OFC_bipolar B_mr421
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 30
Gender: Male
Age of onset (years): 22
Duration of illness (years): 8
Brain pH: 6.1
Post mortem interval (hours): 31
Side of brain: Right
Fluphenazine mg. Equivalents: 60000
Lithium treatment: Yes
Valproate treatment: No
Electroconvulsive therapy: No
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 3
|
none
|
| Sample_geo_accession | GSM123248
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123248/suppl/GSM123248.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123249 | GPL96 |
|
brain_OFC_bipolar B_mr89
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 48
Gender: Male
Age of onset (years): 27
Duration of illness (years): 21
Brain pH: 6.1
Post mortem interval (hours): 13
Side of brain: Right
Fluphenazine mg. Equivalents: 200
Lithium treatment: No
Valproate treatment: No
Electroconvulsive therapy: No
Suicide: Yes
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 3
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 2
|
none
|
| Sample_geo_accession | GSM123249
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123249/suppl/GSM123249.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123250 | GPL96 |
|
brain_OFC_bipolar B_mr91
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 37
Gender: Female
Age of onset (years): 14
Duration of illness (years): 23
Brain pH: 6.5
Post mortem interval (hours): 29
Side of brain: Right
Fluphenazine mg. Equivalents: 1200
Lithium treatment: Yes
Valproate treatment: No
Electroconvulsive therapy: Yes
Suicide: Yes
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 4
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 6
|
none
|
| Sample_geo_accession | GSM123250
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123250/suppl/GSM123250.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123251 | GPL96 |
|
brain_OFC_bipolar B_mr93
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 50
Gender: Female
Age of onset (years): 34
Duration of illness (years): 16
Brain pH: 6.1
Post mortem interval (hours): 18
Side of brain: Left
Fluphenazine mg. Equivalents: 12000
Lithium treatment: No
Valproate treatment: No
Electroconvulsive therapy: No
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 5
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 3
|
none
|
| Sample_geo_accession | GSM123251
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123251/suppl/GSM123251.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123252 | GPL96 |
|
brain_OFC_bipolar B_mr94
|
human post-mortem brain tissue, bipolar disorder
|
Disease_status: Bipolar disorder
Age (years): 30
Gender: Male
Age of onset (years): 7
Duration of illness (years): 23
Brain pH: 5.8
Post mortem interval (hours): 56
Side of brain: Right
Fluphenazine mg. Equivalents: 0
Lithium treatment: No
Valproate treatment: No
Electroconvulsive therapy: No
Suicide: Yes
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 1
|
none
|
| Sample_geo_accession | GSM123252
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123252/suppl/GSM123252.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123253 | GPL96 |
|
brain_OFC_control C_mr131
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 52
Gender: Male
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.5
Post mortem interval (hours): 8
Side of brain: Left
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 1
|
none
|
| Sample_geo_accession | GSM123253
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123253/suppl/GSM123253.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123254 | GPL96 |
|
brain_OFC_control C_mr169
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 53
Gender: Male
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.2
Post mortem interval (hours): 28
Side of brain: Left
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 2
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 2
|
none
|
| Sample_geo_accession | GSM123254
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123254/suppl/GSM123254.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123255 | GPL96 |
|
brain_OFC_control C_mr170
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 52
Gender: Male
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.2
Post mortem interval (hours): 22
Side of brain: Right
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 3
|
none
|
| Sample_geo_accession | GSM123255
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123255/suppl/GSM123255.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123256 | GPL96 |
|
brain_OFC_control C_mr202
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 58
Gender: Male
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.0
Post mortem interval (hours): 27
Side of brain: Left
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 1
|
none
|
| Sample_geo_accession | GSM123256
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123256/suppl/GSM123256.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123257 | GPL96 |
|
brain_OFC_control C_mr206
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 52
Gender: Male
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.5
Post mortem interval (hours): 28
Side of brain: Left
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 2
|
none
|
| Sample_geo_accession | GSM123257
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123257/suppl/GSM123257.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123258 | GPL96 |
|
brain_OFC_control C_mr216
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 44
Gender: Female
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.3
Post mortem interval (hours): 25
Side of brain: Right
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 1
|
none
|
| Sample_geo_accession | GSM123258
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123258/suppl/GSM123258.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123259 | GPL96 |
|
brain_OFC_control C_mr217
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 35
Gender: Female
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.6
Post mortem interval (hours): 23
Side of brain: Right
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 1
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 0
|
none
|
| Sample_geo_accession | GSM123259
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123259/suppl/GSM123259.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123260 | GPL96 |
|
brain_OFC_control C_mr231
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 68
Gender: Female
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.3
Post mortem interval (hours): 13
Side of brain: Left
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 0
|
none
|
| Sample_geo_accession | GSM123260
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123260/suppl/GSM123260.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123261 | GPL96 |
|
brain_OFC_control C_mr350
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 41
Gender: Male
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.0
Post mortem interval (hours): 11
Side of brain: Right
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 1
|
none
|
| Sample_geo_accession | GSM123261
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123261/suppl/GSM123261.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123262 | GPL96 |
|
brain_OFC_control C_mr381
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 42
Gender: Male
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.6
Post mortem interval (hours): 27
Side of brain: Right
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 0
|
none
|
| Sample_geo_accession | GSM123262
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123262/suppl/GSM123262.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
GSM123263 | GPL96 |
|
brain_OFC_control C_mr96
|
human post-mortem brain tissue, healthy control
|
Disease_status: Healthy control
Age (years): 29
Gender: Female
Age of onset (years): N/A
Duration of illness (years): N/A
Brain pH: 6.2
Post mortem interval (hours): 42
Side of brain: Left
Fluphenazine mg. Equivalents: N/A
Lithium treatment: N/A
Valproate treatment: N/A
Electroconvulsive therapy: N/A
Suicide: No
Drug abuse (ratings scale: 0 (no use) to 5 (heavy use)): 0
Alcohol abuse (ratings scale: 0 (no use) to 6 (heavy use)): 0
|
none
|
| Sample_geo_accession | GSM123263
| | Sample_status | Public on Jul 27 2006
| | Sample_submission_date | Jul 25 2006
| | Sample_last_update_date | Jul 26 2006
| | Sample_type | RNA
| | Sample_channel_count | 1
| | Sample_organism_ch1 | Homo sapiens
| | Sample_taxid_ch1 | 9606
| | Sample_biomaterial_provider_ch1 | Dr E Fuller Torrey, Stanley Medical Research Institute, 8401 Connecticut Avenue, Suite 200, Chevy Chase, Maryland, 20815, USA
| | Sample_molecule_ch1 | total RNA
| | Sample_extract_protocol_ch1 | Total RNA was isolated from human postmortem brain tissue using Trizol (Invitrogen, USA) or Tri reagent (Sigma, UK) total RNA isolation kits according to the manufacturer's instructions.
| | Sample_label_ch1 | Biotin
| | Sample_label_protocol_ch1 | Double-stranded cDNA was synthesised from 5 micrograms of total RNA using Superscript II double-stranded cDNA synthesis kit (Invitrogen, USA), purified, then in-vitro transcribed and labelled using BioArray HighYield RNA transcript Labeling Kit (Enzo Life Sciences, USA)
| | Sample_hyb_protocol | Following fragmentation, 15 micrograms of cRNA were hybridised to Affymetrix Human Genome 133A GeneChips for 16 hours at 45oC with constant rotation at 60rpm. Chips were washed and stained according to manufacturer's instructions using the Affymetrix GeneChip Fluidics Station 400.
| | Sample_scan_protocol | Affymetrix HG-U133A GeneChips were scanned with the Agilent GeneArray Scanner
| | Sample_data_processing | The raw data (CEL files) were read into R statistical package and normalised using the robust multi-chip average (RMA) method (Irizarray et al, 'Exploration, normalization and summaries of high density oligonucleotide array probe level data', Biostatistics, 2003).
| | Sample_platform_id | GPL96
| | Sample_contact_name | Sabine,,Bahn
| | Sample_contact_email | sb209@cam.ac.uk
| | Sample_contact_laboratory | Cambridge Centre for Neuropsychiatric Research
| | Sample_contact_institute | University of Cambridge
| | Sample_contact_address | Tennis Court Road
| | Sample_contact_city | Cambridge
| | Sample_contact_zip/postal_code | CB2 1QT
| | Sample_contact_country | United Kingdom
| | Sample_supplementary_file | ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM123nnn/GSM123263/suppl/GSM123263.cel.gz
| | Sample_series_id | GSE5389
| | Sample_series_id | GSE5392
| | Sample_data_row_count | 22283
| | |
|
| |
| |
Make groups for comparisons |
(2 groups will be compared at a time) |
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| Select GSMs and click on "Add groups" |
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