Search results for the GEO ID: GSE6246
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Title
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Description
Characteristics
GSM143330
GPL339
NOR LAK sample III: NMRI mouse on the first day of lactation mammary gland Strain: NMRI, female, mammary gland on the first day of lactation see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143697
GPL339
NOR LAK sample I: NMRI mouse on the first day of lactation mammary gland Strain: NMRI, female, mammary gland on the first day of lactation see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143891
GPL339
NOR LAK sample II: NMRI mouse on the first day of lactation mammary gland Strain: NMRI, female, mammary gland on the first day of lactation see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143903
GPL339
WAP-SVT/t-LAK sample I: WAP-SVT/t mouse on the first day of lactation mammary gland This animal synthesizes the SV40 T/t- antigens selectively in the mammary gland epithelial cells. Strain: NMRI, female, mammary gland on the first day of lactation. see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143904
GPL339
WAP-SVT/t-LAK sample II: WAP-SVT/t mouse on the first day of lactation mammary gland This animal synthesizes the SV40 T/t- antigens selectively in the mammary gland epithelial cells. Strain: NMRI, female, mammary gland on the first day of lactation. see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143906
GPL339
WAP-SVT/t-LAK sample III: WAP-SVT/t mouse on the first day of lactation mammary gland This animal synthesizes the SV40 T/t- antigens selectively in the mammary gland epithelial cells. Strain: NMRI, female, mammary gland on the first day of lactation. see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143908
GPL339
583 tumor 1: WAP-SVT/t breast cancer breast cancer This animal synthesizes the SV40 T/t- antigens selectively in the mammary gland epithelial cells. Strain: NMRI, female, breast cancer. see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143909
GPL339
585pos1 tumor 2: WAP-SVT/t breast cancer breast cancer This animal synthesizes the SV40 T/t- antigens selectively in the mammary gland epithelial cells. Strain: NMRI, female, breast cancer. see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143911
GPL339
597pos7 tumor 3: WAP-SVT/t breast cancer breast cancer This animal synthesizes the SV40 T/t- antigens selectively in the mammary gland epithelial cells. Strain: NMRI, female, breast cancer. see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143913
GPL339
ME-A cells: breast cancer cell line breast cancer cell line Small tissue segments from the 583 tumor 1 were isolated and used to establish the ME-A cells. These cells show continuous T/t-antigen synthesis and are permanently T/t-antigen positive. They exhibit the morphology and growth characteristics of tumor cells. see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143915
GPL339
Revertant ME-B cells: breast cancer cell line breast cancer cell line Small tissue segments from the 583 tumor 1 were isolated and used to establish the revertant ME-B cells. These cells show (in contrast to the ME-A cells) a downregulation of the WAP-SVT/t gene expression. These cells, that were formerly of tumor origin regain the morphology and growth characteristic of non-tumor cells. This transition occurs mostly within the first days after plating under standard tissue culture conditions (DME-medium, 10% FCS). see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
GSM143916
GPL339
Retransformed ME-B-T/t cells: breast cancer cell line breast cancer cell line The revertant-ME-B cells were again reconverted into tumor cells by SV40 T/t. The pSVT/t DNA construct was transfected into revertant-ME-B cells and SV40 T/t-antigen positive cell clones were G418 selected. These clones were collected and designated as retransformed ME-B-T/t cells. The ME-B-T/t cells regained the morphology and growth characteristic of breast cancer cells. see: Klein A, Guhl E, Zollinger R, Tzeng YJ, Wessel R, Hummel M, Graessmann M, Graessmann A. Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals. J Mol Med. 2005 May;83(5):362-76.
 
 
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