Entrez gene ID | | 10000 |
Official gene symbol | | AKT3 |
Full name | | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) |
Aliases | | ,DKFZp434N0250,PKB-GAMMA,PKBG,PRKBG,RAC-PK-gamma,RAC-gamma,STK-2, |
Gene summary | | The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q43-q44 |
Gene position | | 244006553 - 243651535 Map Viewer |
Gene orientation | | minus |
Gene size | | 355019 bp |
Gene sequence |
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OMIM ID | | 611223 |
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