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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NAALAD2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10003
Official gene symbolNAALAD2
Full nameN-acetylated alpha-linked acidic dipeptidase 2
Aliases,MGC116996,MGC26353,NAADALASE2,NAALADASE2,
Gene summaryThis gene is a member of the N-acetylated alpha-linked acidic dipeptidase (NAALADase) gene family. The representative member of this family is the gene encoding human prostate-specific membrane antigen (PSM), which is a marker of prostatic carcinomas and is the first to be shown to possess NAALADase activity. NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG), which is a neuropeptide expressed both in the central nervous systems and in the periphery and is thought to function as a neurotransmitter. The product of this gene is a type II integral membrane protein. Transient transfection of this gene confers both NAALADase and dipetidyl peptidase IV activities to mammalian cells. This gene is highly expressed in ovary and testis as well as within discrete brain areas. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q14.3-q21
Gene position89867818 - 89925779  Map Viewer
Gene orientationplus
Gene size57962 bp
Gene sequence
OMIM ID611636