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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PARP2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10038
Official gene symbolPARP2
Full namepoly (ADP-ribose) polymerase 2
Aliases,ADPRT2,ADPRTL2,ADPRTL3,PARP-2,pADPRT-2,
Gene summaryThis gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q11.2-q12
Gene position20811773 - 20826063  Map Viewer
Gene orientationplus
Gene size14291 bp
Gene sequence
OMIM ID607725