| Entrez gene ID | | 1004 |
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| Official gene symbol | | CDH6 |
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| Full name | | cadherin 6, type 2, K-cadherin (fetal kidney) |
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| Aliases | | ,KCAD, |
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| Gene summary | | This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. [provided by RefSeq] |
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| Location | | Chromosome: 5 Locus: 5p15.1-p14 |
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| Gene position | | 31193796 - 31325237 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 131442 bp |
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| Gene sequence |
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| OMIM ID | | 603007 |
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