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Gene information for CDH8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1006
Official gene symbolCDH8
Full namecadherin 8, type 2
Aliases,Nbla04261,
Gene summaryThis gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q22.1
Gene position62070036 - 61687235  Map Viewer
Gene orientationminus
Gene size382802 bp
Gene sequence
OMIM ID603008