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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL18BP (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 10068 Official gene symbol IL18BP Full name interleukin 18 binding protein Aliases ,IL18BPa, Gene summary The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq] Location Chromosome: 11   Locus: 11q13 Gene position 71709958 - 71713574  Map Viewer Gene orientation plus Gene size 3617 bp Gene sequence >IL18BP:17015753..17019369:Length=3617 TTTCCTGTGGTGGGTTCACACGCAGCTAGACACAGCTAACTTGAGTCTTGGAGCTCCTAG AGGGAAGCTTCTGGAAAGGAAGGCTCTTCAGGACCTCTTAGGAGCCAGGTAGGAGTCTGG GACTACTAGTGAACCTAGACCTGTGGCTCTGGCCAGAGGGGCTAGGATGAGAGACAGAGG GTGTGATGGTGGGTGCTGGGAGATGTAGCCGACCTTGGGGCTGGTGGCTGGGGGAGTGGG TAGCCTGGGAAAGGCCAGGATGTGGACGGACTGGTATGGCATTGAGCCTGAAGTGGTCCA ACTTGGGGTTCCCCAGTGCCTAGGAAAGTTGTCCCCTTGAATGTCAGTGTGAAGGTGAAG GAGGAAGCAGATGCCTGTTCATATGGAAACAAAGACCTGGCTGTGAAGAGGGGAGGCGGA CACCAAAGTCCTGACACTTGGGCGGGACAGAATTGATCTGTGAGAGACTCATCTAGTTCA TACCCTAGGTGACCCTGGGGGTGGCATGGGGGTAGATTAGAGATCCCAGTCTGGTATCCT CTGGAGAGTAGGAGTCCCAGGAGCTGAAGGTTTCTGGCCACTGAACTTTGGCTAAAGCAG AGGTGTCACAGCTGCTCAAGATTCCCTGGTTAAAAAGTGAAAGTGAAATAGAGGGTCGGG GCAGTGCTTTCCCAGAAGGATTGCTCGGCATCCTGCCCTTCCCAGAAGCAGCTCTGGTGC TGAAGAGAGCACTGCCTCCCTGTGTGACTGGGTGAGTCCATATTCTCTCTTTGGGTCTCA ATTTTGCCTTCCCTAATGAAGGGGTAAGATTGGACTAGGTAAGCATCTTACAACCATTTG TGGTCATGAGAGCTGGGGTGGGGAAGGATTGTCACTTGACCCCCCCAGCTCTGTTTCTAA GTGCTGAAAGAGCTCCAGGCTATGCTACGGGAGGAGAAGCCAGCTACTGAGGAAAAGCCA GCTACTGAGAAAAAGCGGGAGTGGTTTACCATTCTCCTCCCCCACCTTTCACCAGAGAAG AGGACGTTGTCACAGATAAAGAGCCAGGCTCACCAGCTCCTGACGCATGCATCATGACCA TGAGACACAACTGGACACCAGGTAGGCCTTGGGGCTACGCATGGGCAGGCGGGGTAGGGT GAGGTCTATGAACAGAATGGAGCAATGGGCTAACCCGGAGCCTTCACTCCAAGGCAAACC ACCCAGCGCACCTGGTGCTGTTGCTTTAAGAACCTGGGCAGATATTGTAGCTCTGGCTCC AGTCTAAAGCTTCTCTGTACTCTGTTCAATAAAGGGCTAAGGGGTGGGTGCTGAGGGGTC CCTCTTCCCGCTCTGATTCCCTGGCTAGAACCCAGACATCTCTGGGCTGGAGTTACATCC TTACCCGGGCAGCCCACTCTGTCTCCAGAGCCGCTGACCTGTAACTGTCCTTTCCTCAGA CCTCAGCCCTTTGTGGGTCCTGCTCCTGTGTGCCCACGTCGTCACTCTCCTGGTCAGAGC CACACCTGTCTCGCAGACCACCACAGCTGCCACTGCCTCAGTTAGAAGCACAAAGGACCC CTGCCCCTCCCAGCCCCCAGTGTTCCCAGCAGCTAAGCAGTGTCCAGCATTGGAAGTGAC CTGGCCAGAGGTGGAAGTGCCACTGAGTAAGAAGCACAGTGGTGGAGGGTGGGCTATGGG CACAGAGGTTCCCAGGGTCGGGTTGACTCCTGAGCGCCAGTCCCCTTCTGCCCATGTACC ACCAGCTGAGCCAGCTGGGCTGAGCACGCACCATTCTCCCTCCCCAACCCAGTGTCATGG GTGCAGGCTTGGCGCAGCTCCCAAGATGCTCCCTATCAAATAGGACAGAGAACTCAAGAC ATAAGTAATGGTCACAGGACCTCCCAGAGCCTTGGTTGCAGTGGACCCCAAGGCCAGCCC CTCCACCCAGAGCCTGCTGGCCTCTGGCCATCTCAGAGGAGCAGCAGCCATCCAGCACTG CCTTTGTCACCTGGGCTCCCAAGTCACCGAGGCTGGGCACTAGAAAAGGTCATCCTGAGG AGACAGGTTCAGAAGAGGATTCATCACGTGAACCAAGGACCATTCCTCACATTCCCCGTG TTTAGGGCTAGGGCCTCTCGGAGACAACTGCACTTCTGTAACGGACGTTCCCACCTAGGT GGTGTGCAGAGCAGTTCTCTAGGTTCCAGATGCATGGGGACTGGGGGGAGCTGGCAGGGA GGGCACAGCAGAGCAGGGTAGGGGAAGGGCCTGCTCTTCTGAAGAGCTAACTGCTGCCTG TGTCCCTAGATGGAACGCTGAGCTTATCCTGTGTGGCCTGCAGCCGCTTCCCCAACTTCA GCATCCTCTACTGGCTGGGCAATGGTTCCTTCATTGAGCACCTCCCAGGCCGACTGTGGG AGGGGAGCACCAGGTGAGGGTCGCAGCAGCCAGGTGGGTGGGAAGGAGGCCTTCTGCGGC CTTCTCATGACCTTTCCTTCCCTTCCGCTCCAGCCGGGAACGTGGGAGCACAGGTACGCA GCTGTGCAAGGCCTTGGTGCTGGAGCAGCTGACCCCTGCCCTGCACAGCACCAACTTCTC CTGTGTGCTCGTGGACCCTGAACAGGTTGTCCAGCGTCACGTCGTCCTGGCCCAGCTCTG GGTGAGGAGCCCAAGGAGAGGCCTCCAGGAACAGGAGGAGCTCTGCTTCCATATGTGGGG AGGAAAGGGTGGGCTCTGCCAGAGCAGCCTGTGAACTAATGCCCAGCATTCCTCAAGGTC AGCCAGACAAAAAGGAACTTAGGTCTTGGGCAGAGGAGGTGTAGCCTGGGGCAAAGTGAT GAGATGTCCCTCCTTTCCTTGGCCTGATCCTTGTCTGCCTTCACTTCCCTAGGCTGGGCT GAGGGCAACCTTGCCCCCCACCCAAGAAGCCCTGCCCTCCAGCCACAGCAGTCCACAGCA GCAGGGTTAAGACTCAGCACAGGGCCAGCAGCAGCACAACCTTGACCAGAGCTTGGGTCC TACCTGTCTACCTGGAGTGAACAGTCCCTGACTGCCTGTAGGCTGCGTGGATGCGCAACA CACCCCCTCCTTCTCTGCTTTGGGTCCCTTCTCTCACCAAATTCAAACTCCATTCCCACC TACCTAGAAAATCACAGCCTCCTTATAATGCCTCCTCCTCCTGCCATTCTCTCTCCACCT ATCCATTAGCCTTCCTAACGTCCTACTCCTCACACTGCTCTACTGCTCAGAAACCACCAA GACTGTTGATGCCTTAGCCTTGCACTCCAGGGCCCTACCTGCATTTCCCACATGACTTTC TGGAAGCCTCCCAACTATTCTTGCTTTTCCCAGACAGCTCCCACTCCCATGTCTCTGCTC ATTTAGTCCCGTCTTCCTCACCGCCCCAGCAGGGGAACGCTCAAGCCTGGTTGAAATGCT GCCTCTTCAGTGAAGTCATCCTCTTTCAGCTCTGGCCGCATTCTGCAGACTTCCTATCTT CGTGCTGTATGTTTTTTTTTTCCCCCTTCACTCTAATGGACTGTTCCAGGGAAGGGATGG GGGCAGCAGCTGCTTCGGATCCACACTGTATCTGTGTCATCCCCACATGGGTCCTCATAA AGGATTATTCAATGGAG OMIM ID 604113