Entrez gene ID | | 10072 |
Official gene symbol | | DPP3 |
Full name | | dipeptidyl-peptidase 3 |
Aliases | | ,DPPIII,FLJ11387,FLJ22331, |
Gene summary | | This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q12-q13.1 |
Gene position | | 66247880 - 66277130 Map Viewer |
Gene orientation | | plus |
Gene size | | 29251 bp |
Gene sequence |
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OMIM ID | | 606818 |