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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDH10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1008
Official gene symbolCDH10
Full namecadherin 10, type 2 (T2-cadherin)
Aliases,-,
Gene summaryThis gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
LocationChromosome: 5   Locus: 5p14-p13
Gene position24645085 - 24487209  Map Viewer
Gene orientationminus
Gene size157877 bp
Gene sequence