Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACTR1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10120
Official gene symbolACTR1B
Full nameARP1 actin-related protein 1 homolog B, centractin beta (yeast)
Aliases,ARP1B,CTRN2,PC3,
Gene summaryThis gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q11.1-q11.2
Gene position98280561 - 98272402  Map Viewer
Gene orientationminus
Gene size8160 bp
Gene sequence
OMIM ID605144