Entrez gene ID | | 10120 |
Official gene symbol | | ACTR1B |
Full name | | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
Aliases | | ,ARP1B,CTRN2,PC3, |
Gene summary | | This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q11.1-q11.2 |
Gene position | | 98280561 - 98272402 Map Viewer |
Gene orientation | | minus |
Gene size | | 8160 bp |
Gene sequence |
| |
OMIM ID | | 605144 |
|