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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for YAF2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10138
Official gene symbolYAF2
Full nameYY1 associated factor 2
Aliases,MGC41856,
Gene summaryThe protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q12
Gene position42632154 - 42550906  Map Viewer
Gene orientationminus
Gene size81249 bp
Gene sequence
OMIM ID607534