Entrez gene ID | | 10138 |
Official gene symbol | | YAF2 |
Full name | | YY1 associated factor 2 |
Aliases | | ,MGC41856, |
Gene summary | | The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q12 |
Gene position | | 42632154 - 42550906 Map Viewer |
Gene orientation | | minus |
Gene size | | 81249 bp |
Gene sequence |
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OMIM ID | | 607534 |
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