Entrez gene ID | | 10156 |
Official gene symbol | | RASA4 |
Full name | | RAS p21 protein activator 4 |
Aliases | | ,CAPRI,FLJ59070,GAPL,KIAA0538,MGC131890, |
Gene summary | | This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7q22 |
Gene position | | 102257205 - 102220093 Map Viewer |
Gene orientation | | minus |
Gene size | | 37113 bp |
Gene sequence |
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OMIM ID | | 607943 |
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