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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RASA4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10156
Official gene symbolRASA4
Full nameRAS p21 protein activator 4
Aliases,CAPRI,FLJ59070,GAPL,KIAA0538,MGC131890,
Gene summaryThis gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q22
Gene position102257205 - 102220093  Map Viewer
Gene orientationminus
Gene size37113 bp
Gene sequence
OMIM ID607943