Entrez gene ID | | 10219 |
Official gene symbol | | KLRG1 |
Full name | | killer cell lectin-like receptor subfamily G, member 1 |
Aliases | | ,2F1,CLEC15A,MAFA,MAFA-2F1,MAFA-L,MAFA-LIKE,MGC13600, |
Gene summary | | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12p12-p13 |
Gene position | | 9142221 - 9163343 Map Viewer |
Gene orientation | | plus |
Gene size | | 21123 bp |
Gene sequence |
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OMIM ID | | 604874 |
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