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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GDF11 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 10220 Official gene symbol GDF11 Full name growth differentiation factor 11 Aliases ,BMP-11,BMP11, Gene summary The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq] Location Chromosome: 12   Locus: 12q13.2 Gene position 56137064 - 56146665  Map Viewer Gene orientation plus Gene size 9602 bp Gene sequence >GDF11:18280370..18289971:Length=9602 TCCCCGCCCCCCAGTCCTCCCTCCCCTCCCCTCCAGCATGGTGCTCGCGGCCCCGCTGCT GCTGGGCTTCCTGCTCCTCGCCCTGGAGCTGCGGCCCCGGGGGGAGGCGGCCGAGGGCCC CGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCAGCGGCGGGGGTCGGGGGGGAGCGCTC CAGCCGGCCAGCCCCGTCCGTGGCGCCCGAGCCGGACGGCTGCCCCGTGTGCGTTTGGCG GCAGCACAGCCGCGAGCTGCGCCTAGAGAGCATCAAGTCGCAGATCTTGAGCAAACTGCG GCTCAAGGAGGCGCCCAACATCAGCCGCGAGGTGGTGAAGCAGCTGCTGCCCAAGGCGCC GCCGCTGCAGCAGATCCTGGACCTACACGACTTCCAGGGCGACGCGCTGCAGCCCGAGGA CTTCCTGGAGGAGGACGAGTACCACGCCACCACCGAGACCGTCATTAGCATGGCCCAGGA GAGTAAGTGGGCTGCGGGGCGCGAGCAGTGGGGTGCTGGCTCTGGCCCCGCGAAGGGCGC CTTCTGCTCCAAGCGGGGCGCTCCCTGCTGCCCCGGCCCGGAAGCTTTTTCTGCGAAAAC TTGACGAATTAGGGAGCGGGGGCTACTTCATAGAAGTTTTCCGAGCGGTGGAGATGGGCT GCAAAGTTGTATGCACGCCTAGTTCCCGGAGGTTGGGGCGGGGGAAATGGGGCGGGTTTC GAGATAGTGCCTTCCACCCCCAGTATGCTAAAAAGATCCTTGTTGGAGTCCGGGGAAGCT GGGGCTGGGCAGTGACTCTGTCCTGAAAAGCCGTGGTGGGGAGGCTGGAGAACAGAATCG GGAGGCTGCAGGACCCCCGCAGCCCCAGCTGGACTGCAGTGCTCTCTGCTTCCCAGTGGC CCTGGCGGTAACTCCCCACTCCGTGCTCCGTTCGCAACGTGCCCAACGGGTTGCAGAGAA CTGTGTGCTTTCTCCCAAGAATAGGGTCCCAGAGCCCTGTACACCTCCTGGCAGCCCAGC TGGCACCCTTTCCATCCTGACCCCTGTCTCAGACCGGGTATCCCAAGGGGTCGGAAAAGC TGTGCCTTCTTGATACTGACCGAGCTCGGAGAGCTCAACTCCATTGCGCTGGGGGCTAAG GACACTCATTGGCTACTCAAACCTTAGTGTTCCATCCCTTATTCGCCCACCCCTACCGCA GGTGGACTTGAGAGAGACGAAGACCTAGGAAAAAAGAGAAAGTAGTAGATGGGGGAGCAG GAACCCAGGCATCCGAGCCCCTGACCAAACGGAAGATGAACATATAATAGACATGAGCTG CTTTGAAATTTTATGGCCTGGAAAATCCAGGCGAATACTACACCCCCCCTTTTCCAGCTC TCCTTAGGGTCAGGTGACTCCTTCTCCTCCCCCACTGAGGTCTCCCCCCCTCCCCAACTA CAGGGAACCAGGCCTCTCTTATTCCCTAGTGGTTTGGCAAGGTTCCCCCCTTCCCACAGC CCCCTGCAACACACACAGAGTTTGGTTTTATGGCTGTGAACAGAAGACGGGGGAGACTGG TTTATTGGCAGATGGGTCATAAAAAGCTGGGGGCTGAGGGGAGTCCCAGTGGCCCACCCC CATGGGAGAGGCACAGGAACCCAGGTGTGCATCTGGGAGGCTGAGTGCCTCACACTGCCC CTGGTATTTCTGCAGACCTCAATTCCACAAGACTTGGTCAGGGCTGTTAAACTCAAAGAA CCAGGAAACTGGCTGTGGGGGTGGGAGGTATGGGGATCCGGTCTGGGGTTCCTCAGTTTC CCTTCTATTCTTAAGCCTTCTGCTTATGGAAGCTAGGGTCAGTCTCAGATCGACTGAGGG CAGGGGTAGGGGGTGGGGTTTCTAGGAAACAGAGTTATAGAGGAATTCAGATCAAGAGTT TGCTGGAAGATGAAGGTTACAGAGGGAAAAGATACTCTAGTCTCTGTGGTGTAGTGTGTG TGAAGATTTCCAGGATGGGTGATGGGGCTGTGGACTTCTCCTTGCCCCTAAATATCCTTA GCATCCCTTAACCAACAGGCCTGAGCCCACCAGAGTTAGCTCTGGTAATGGGGATACACG AAGTGAAGGGACCCTGCCTTCATGAGTTGGGCTGTGCAGGTGAGGCCTGGGTCGGTGGGA AGGGGACACCAGCTGGTAGGATCCCATCAAAACTTACAGTCCCGTGCCACCCCAGGACTT GTACAAGTAGGGAACTGGGTCTCCGGCCAGGTATTGTACGTCCCCTTTAAGAGCCTAGCT GAGCTCTTAAGAGAGGGAGGGGGAGTGGAGGGGAGGGGAGGGAGAGAGGGGAAAAGGAAA AAGAGACTTTTATAGTCTAATCCCCAGGGACCCGCTTTAATAAGAGACTTGTGCTCTGCT AATCGGGGGAGGTGTTTGTCAGCAGAGATGGCCTCCGTTCCCCTCCCCCTCCCTCCCCTC CCCCAGCCCTCAACCCTGGACCCCAGCCCCCACCTCTCCTAGGCTGCTCTGCCTGCCCTA GTTCCCTCTACCCTCTCAGGCTCTCCCACCAAGCCTTCATCCTGGGAACCCAGCCCCCTG CCCTTCTGGGAGCCAAGCCCAGCCCGAGTTTCTCTCTCCTCCCCACACCAAGAGGCCCCT GCCCTCTCAGCCCAACCTCCTGCCCTTAGGCCTTCCAGCCATGGTTGGGAGTGTGTGTGT TTGGGGGGGTTAGGGTGGGGGGAAGGGGAGGTGGTGTGCAGGGAGGGGGTTGGGCATTTG CTGAAAATAGTGCAGTGACCTCTCTCTCCCACCAGCGCCGCCTACTAAACCTGACCTGCT GCCTGCCACCAGCCCGATCAATTCAACACAGATGTGGCCCCTTTTCCTCCCCATCAGAGC TCGGCATATGTGTGCTGGGTACTCTCTCGAGCCCCGTTTCCCTCTGTGGCTCTACCTGCT TCTCCTTTGTTCCTCAGTCTGTACCCTTTCTATCCTTTCTCTCCTTTACCCCACTAGGTT TAGCTTCCTCCCACCTTTAGCTTTCTAACCATCACCCACTCCTTTCTATCACTGCCTCTG CATCAGGATTCTCAAACTCTCAAACTTATTCTCCCTTTGCCATGATTATCCCCTGCATCT TTCCACTCTAACTTCTATTTCTCTCCCTATATCTACTAATATGCCTTCAACTCTTAACAG TCTCTTCTCTATTATCTCCCTCACCATCTCCAGTCTCTCCCCTGGCTCTTCTCCCTGCTC TTTTCTTTCTCCCTATGTTCTACCTCCTTGTAGCACTGACTGTCCCCTGTCCACTGGGAC AAGTATGTGGAACCAAAGACTTAGATGTAGCCCTCATCTTCAAACCCTGGATCAGCTTAG GTAGAGGGAGGGTTATGTTTAGAGCTTAGTAGAGAATGCGAAAATAGTAGTAGCTTCTCA ATAAATGTTGGTTTGTTTGTTTCCTATTTTCACATTCTCTAGTTAATGCTCAGCACTCAT GTGAAGCAAGAATTATTATTATCTGTATCACACTGAGAAGTTTGGTGAGTAAGGTTAGAT AGTGGTTAGTAAGGAATCAGGCAGTGATTAAACCCACTTCAATTATAGCCAAAGAACAGA ATTTAGATGCCAGGAAGAACTTTCAGGCACTTGCCTGTATAATTTAAGATTGGGAGTTTA GGGAGTTCATTCACCATGTATTTATTGAGTGCTGTCTAGCACTATGGGAGGCACTGAAGC TACAATGGTGAGCAAAACAGACACAGTATGAATAACAACAGTGTCCACTCTCATGGAGAT TAGTACCTAATGGCAAGAAAATAGACAATTCTTATGCTGAAATTTGTAAAGTATGCTATT TGGGATGTTGCTTGTCACTCCCCATCTCACTAGTAGCTTCCCTATCCCAGCTACTTCTGA TCTCTGAATTCTCACCCCCCAAACCCTACTCCATTGCACCATCACTGAAGCTCCAGCCAG TAAAATAACTGGACTACCAGGGCCCTGGGACCTCAGAGAATAATCAAGAAAAAAAAAAGC TATAGAGACTTTGGGTATCATATCCTGAATATATGAAGTTCATTAAGCACTTTCTCCTCA TCTCCCTTAGAAGGTCCTCTTTCTCCCAGGGTGGGGGTGGGGAAGAGCTGACAGGACACC CTAAGTCCATCCTGATTTTGCAGAACTCAAGACATGGGGAGGATACTTAAAGGCCTAGAC TTCCTAACCCTGCTTATATGGCTCTGGAAGCTCATTCCTGATTCTTCCTATCTAGAGTCA GGATAGACATATTCTGTCCAATGGAGACATGTTGTAGGACACTCCCAACTGACTTAGGAA AGGCAGTGAAGAGGAGCTGGAATGGAGGCAGAGGCAGATATTTATTGAGAATCATCTATT AGACCCAAGAAGGATCAATTTAAGGTCCAGAGCAAGGGGAAATGGGTCAAAATGTAAAGT TGGGATGTTCAAACTTTGTAAAGACCTACTGGCACTAGACTGAGAAGTCAAAGGAAGCTC AGGGGAGAAAAAAGGCATTGTAGTTAATCTGGTGTATTTAATATTATTTCTGGTGCTTTA GGCAAATAGGAGGCAACACCATGGAGGTAATTATTCCTTTCCTCAAGAGCTGGGGGCAGT CATGGTGATGATGATGGAGCAGCAGCTGAAGAAACTTCTTAAGAGAGAATGGGGAGACAG ATGTATAGGAAGTGCTTGGATAGTTCCATTTTGCTGGGTGTTATTCCTAATGGGAGTGAG GCAAGAAGCCTAGATCTGAATTCTGGTTTACATAATGGGATAAATTTAGCTCATGCTCCC TATCTGGACCCTGGGTTATCCCCTCTCTGAGGCCATCTGTGTTATTTTGTGGGGGAGGGA TGTGCCAGGCTCTACCTGTCCAGCAGATAAATCAGAGCAGATAGGGGAAAGGTGATGGAA GGGCAGCAGGTGTGATAAGAGGTATGGCTTCTATAAAGAGCTTCAAAGATTCAGAAAATG TTGGAGCCTTATATGCTGGGAAAAGTTGGACAGTAAGGATGGTGGTGGATGAATAATTTT GCAGGTTATCTGGTAGACAGGAACCTATATATTAGGGCAAATGGATTAGGAAATGGACAC AGATCAGTAAGGCCTTATAGGGCCATCATCCTAAAGAGGAAGTGCTGTTTTAGGTACCGG AGACATGGTATAAGATAGGCATGGGAGAAGGGTAAAGAAGAACTGGAAAATCAGGCTGAG AAGTCCAAAATTGCCAGTGCCACCCAGGACTACTGATCCCCTACACAAACACCCTTTGCT GATGCTGTGCCCTTCTCTCTTATCAGCGGACCCAGCAGTACAGACAGATGGCAGCCCTCT CTGCTGCCATTTTCACTTCAGCCCCAAGGTGATGTTCACAAAGGTACTGAAGGCCCAGCT GTGGGTGTACCTACGGCCTGTACCCCGCCCAGCCACAGTCTACCTGCAGATCTTGCGACT AAAACCCCTAACTGGGGAAGGGACCGCAGGGGGAGGGGGCGGAGGCCGGCGTCACATCCG TATCCGCTCACTGAAGATTGAGCTGCACTCACGCTCAGGCCATTGGCAGAGCATCGACTT CAAGCAAGTGCTACACAGCTGGTTCCGCCAGCCACAGAGCAACTGGGGCATCGAGATCAA CGCCTTTGATCCCAGTGGCACAGACCTGGCTGTCACCTCCCTGGGGCCGGGAGCCGAGGG GCTGGTGAGCAGGGGGCCTGAGGTGGTGGATATGTGTAACCTGGCCCTGAGGAGATAGGG TTACATTGGAAAAGGTAGACAAGGAATGTGAAGGAGGTTGGGGACCAGCATTACTTCTCT GGGGTCAGCAGCTGATTCTAGAGGAGGAGGTGAGGAGTGGGGTGGCAACTATTACTTCTC AAGGATCCAAATCAGACAACAGCTGAAAACTGGATTTGAAGGTAAAGGTGTCAGTTAATG GAAGAGCTGTGAGAACAAAAAAACTGGCTGTTGAGGCGTTGGGCCAAGGGGCTGACAGGG ATCAGGTTGCCAGAAGAGTAAGAATTAGAGATGGTGAGTTGAAGGAGAGCTAGCTAGCTG GCAAGAAAAGTGGGCAAAAGATAAATTCTGGGGGTGGGAGCAATGGAAAAGCTGAGAAGT CAGCAGTCTCTATTCTGATGCCCCTGGCAGGTGGGAAAGGAACAGGGAAGAGGAACTGTT CAGGACCATATCACATTTCTTTCCCCTCTCCCTGACCCTCAGCATCCATTCATGGAGCTT CGAGTCCTAGAGAACACAAAACGTTCCCGGCGGAACCTGGGTCTGGACTGCGACGAGCAC TCAAGCGAGTCCCGCTGCTGCCGATATCCCCTCACAGTGGACTTTGAGGCTTTCGGCTGG GACTGGATCATCGCACCTAAGCGCTACAAGGCCAACTACTGCTCCGGCCAGTGCGAGTAC ATGTTCATGCAAAAATATCCGCATACCCATTTGGTGCAGCAGGCCAATCCAAGAGGCTCT GCTGGGCCCTGTTGTACCCCCACCAAGATGTCCCCAATCAACATGCTCTACTTCAATGAC AAGCAGCAGATTATCTACGGCAAGATCCCTGGCATGGTGGTGGATCGCTGTGGCTGCTCT TAAGGTGGGGGATAGAGGATGCCTCCCCCACAGACCCTACCCCAAGACCCCTAGCCCTGC CCCCATCCCCCCAAGCCCTAGAGCTCCCTCCACTCTTCCCGCGAACATCACACCGTTCCC CGACCAAGCCGTGTGCAATACAACAGAGGGAGGCAGGTGGGAATTGAGGGTGAGGGGTTT GGGGGAAAGGGGAAGCAGGGGCATAGTCAGGGTGGGGAGTGTTTGAAGTTTGCAGATGAG AAGGTTTGACAAAAAGACAGAGAGATGTAGAGACAGTGATAGAGACAGAGGAACAAAAAG AGCAGCAGTGAGAAGGCAAAGAGAGAGGCAGAAGAGACAGACGAGGCAGAGACAAAACAC TGAGAAAGAGACTGAAATGGAGTAATAAATGAAAGCCCCACACCAAGCCTCCTTTCTTCC ACTGGCAAGGTGAGGGGCTTGGTATAGTTTGGGGAGATCCCCTGACTATTCAGTAGGAGA AGAAATCAAAAATCCATTCTTTTCTCCTTCTCTCCCTCCAACAGTGGCCAGGGGAAGGGG AAGTGAGGGCAGGGGCAAAAAGATTTGGGAATTTTTATTTATTTATTTATTGTGACTTTT CATTTTTTTGGTATTTGGCTTTACTGGAATAGGAGGGCCCCTGCCCACTGTGCCCCGTTT ATCCCTTATTCCCCAAACCCTGCTCTCCCCAACACCTACTCACTTAAGCACTTGTATAAA GCCTCCAGGGTTGGGAATGGGAGTAAAGGGCAAGAGGGCGGACACATGAAGTTTAGTTTC TAACCCATCATCACCCTAACTCAACCTTTTCTGAGCCAAATGGCTTGAATTGAAGCCAGT TGTCATGGAAATAGTAAGAGGTTAGGGTTTAAGAGCTGGGGATGCGGGGGTGGGAGAGAG AACCCTCAACATCCAGGATCTATATAATGAGAGCTACTTTAAACCCTCAGGTCCACCCTC ATGATGCTGAGTTATTTAGCCAGAGGGTGCAGCCTGCTTATGCCCAAATTCCCTCAGCCA AGAGAGAGACCAAAGAGCCTCTGGAATGGCCCTGCTCCCAGCCTCTATCTTCAGGTCAAT TAGAGAGAGTATAGAGACCCCAGAGTCCCCTGGGTCTGGAAAGCGTTAGGAGAGGTCAAG AAAGGAGCAGTAAGGAGGCTGAAGGTTACAGGGCATTTGAATCCAAATCACTGCTCTGGG CTAGGGAATAGAGCCAGCAGACCAAGGTGGGAAGGATTCTGGAAGGGGGACATTTTAGTC TCCTAACCCCAAAGCTCAGGGTGGAAGAGGGGAGAACAAGGAAGCAGAGTGTATAATTAT TTTTTCCTTTTATTTTTGGAATCTAACAGTACCTGGCAGCAGGGAGGGGAAAGTACAGTG GGGAAAAGCATCTGACAAGGCCAGTTAGAACAGAGGATGGGAAGGATGGAGACTCCCGGG CTTGGAAGGCTAGGAAGCAGGCAGAGACTGGTTGCCATTTCAAGTCACTAGCTAGGCCCA TTCATTCCTCCCACAACCCTGACCCATTCTCCTCTGGACTCACTGTGCCTCAGTTTCTTC CCCTCAATGGAATGAGAAATGACAGCACCCGCCACAGCCAAGAGATGAATTCTGAGCACT TACCACGGGCACTTTATGGACATAAAATACCTCTCGCTGTGGGACAGATAACCAGGGCAC CAGAGTAGTGGTGAAGAGATGTGAGGCTTAAGAGGAGTCACAGGCTTCAGAGTACAAGTT CCCCTCTGCCTCCCAGCTGGACAGTGCCTAGAAGCCAAGGAGTTGAGAATCTCCTGATCC ACACCCTATCCTTACTTCACCACCAGGCCTCTTGGCTCCAGGCAAGAGCTTAGAGGATGT CAGGAGAGGTGGGGGTAAGAATCTTCAGCAAAACTGTCACTCTAAGTAGAGCCAGCAGTT ACGGGTCTGATAAAAACAGTACTGAACTAAAGTAAAGCCCAAGCTGGTGAGCAAAACTGG ATGGCTCATTCTTCCCAAGAGCATGACTCTCCCCCTTGGCCAGTTGGTGGAAGGGGCAAA GGTATGTGACCACCCTTGAGAAGGTGATGTTGGTGAGCTTTAACATCTTATTCCTATTCT TATAGTGAGAAAGTGAAACAAGATCTTTCAGTAGAGGAATGGGCAGGGCTGTTAGGCTCT TCAGCTTGCCTTCACCCATATAGCAGCTATGCTAACCCCAAGCCTCTCTGGCCCTGTTCT TCATCCTTCCTTCTGCCCCAATCCTGAAGGACAAGACACACCCGGCCATCAACACCACTC ACATTTCCTTGGTGGAAGGAAAGGAACAGAGAAGTGAAGAACAGATACCTCCCTCCAAGG TCAAATGCCTCGTGATCTTGGCAGAGTAGGGATTGGGCAATAAGCATCAGGTATCTTCCC TCTACAGATTCTAGAGAGCTGGGGCATTAAATATGGGGGACACTTAGAATACAGCTCCTT AAATACCACCAAATAAAGACCTTTGTGTGTGTGTGGTGGGTGGGGGGGGGGCAGGGGTCT TTCTCTTATGAACATAAATCTGTGAGCTGAAGTCTCATTCCCCTGTTCCTCCCTACCCCC AAAGAGGCACAGAGTGAAGGGACTTGGGGGGCACAGCTCAGCAACCCAGTGGGAGTTAGC ACCCCCTCCCACCTTATGATGTGTGTGGACCTGGCCAGTGCCCCTCTGAACATATCATTA TTAGTGTAATTATCATTTATTTTGTGTATTTGTCACATTGTGTGCATGACAGCCTTTGTT AAGGGTGTCTGAGGAGTATGGAGCTGACAGGGGCATTGGAATGCCAGGAAAGAACTTCTT CAACTGAGATCAAGGCTTCCTGGAGGGAACCACTGCAAAAAGGCCATCAGGCAGTTTTCA AGTTATGTGACAGAGGGCAAAGACGGCCATAGGGTGCTCTGAGTTTTGGGATGGTCACAT GACACAATCCAGCACTTGAACCTGAAAAAAAAAATAAAAGCGGTCAAAGAGTTTAGAATT CA OMIM ID 603936