Entrez gene ID | | 10230 |
Official gene symbol | | NBR2 |
Full name | | neighbor of BRCA1 gene 2 (non-protein coding) |
Aliases | | ,DKFZp686F081,MGC104305,NCRNA00192, |
Gene summary | | This gene was identified by its close proximity on chromosome 17 to tumor suppressor gene BRCA1. Experimental evidence indicates that the two genes share a bi-directional promoter. Transcription for either gene is controlled individually by distinct transcriptional repressor factors. A short (112 amino acid) open reading frame is observed which includes a region derived from a LINE1 element. A strong Kozak signal is not observed for the putative ORF and the stop codon is more than 55 bases upstream of the last splice site for the transcript suggesting that the transcript is subject to nonsense-mediated decay. Therefore, this gene does not appear to encode a protein. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q21 |
Gene position | | 41277600 - 41297130 Map Viewer |
Gene orientation | | plus |
Gene size | | 19531 bp |
Gene sequence |
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