Entrez gene ID | | 10235 |
Official gene symbol | | RASGRP2 |
Full name | | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
Aliases | | ,CALDAG-GEFI,CDC25L, |
Gene summary | | The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13 |
Gene position | | 64512928 - 64494383 Map Viewer |
Gene orientation | | minus |
Gene size | | 18546 bp |
Gene sequence |
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OMIM ID | | 605577 |
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