Entrez gene ID | | 10254 |
Official gene symbol | | STAM2 |
Full name | | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
Aliases | | ,DKFZp564C047,Hbp,STAM2A,STAM2B, |
Gene summary | | The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q23.3 |
Gene position | | 153032506 - 152973315 Map Viewer |
Gene orientation | | minus |
Gene size | | 59192 bp |
Gene sequence |
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OMIM ID | | 606244 |