Entrez gene ID | | 10262 |
Official gene symbol | | SF3B4 |
Full name | | splicing factor 3b, subunit 4, 49kDa |
Aliases | | ,Hsh49,MGC10828,SAP49,SF3b49, |
Gene summary | | This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q12-q21 |
Gene position | | 149899702 - 149895211 Map Viewer |
Gene orientation | | minus |
Gene size | | 4492 bp |
Gene sequence |
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OMIM ID | | 605593 |
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