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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RAMP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10267
Official gene symbolRAMP1
Full namereceptor (G protein-coupled) activity modifying protein 1
Aliases,-,
Gene summaryThe protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q36-q37.1
Gene position238768187 - 238820756  Map Viewer
Gene orientationplus
Gene size52570 bp
Gene sequence