Entrez gene ID | | 10284 |
Official gene symbol | | SAP18 |
Full name | | Sin3A-associated protein, 18kDa |
Aliases | | ,2HOR0202,MGC27131,SAP18P, |
Gene summary | | Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq] |
Location | | Chromosome: 13 Locus: 13q12.11 |
Gene position | | 21714653 - 21723224 Map Viewer |
Gene orientation | | plus |
Gene size | | 8572 bp |
Gene sequence |
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OMIM ID | | 602949 |
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