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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SAP18 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10284
Official gene symbolSAP18
Full nameSin3A-associated protein, 18kDa
Aliases,2HOR0202,MGC27131,SAP18P,
Gene summaryHistone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq]
LocationChromosome: 13   Locus: 13q12.11
Gene position21714653 - 21723224  Map Viewer
Gene orientationplus
Gene size8572 bp
Gene sequence
OMIM ID602949