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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDKN2C (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1031 Official gene symbol CDKN2C Full name cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Aliases ,INK4C,p18,p18-INK4C, Gene summary The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq] Location Chromosome: 1   Locus: 1p32 Gene position 51434367 - 51440309  Map Viewer Gene orientation plus Gene size 5943 bp Gene sequence >CDKN2C:21406285..21412227:Length=5943 CTCTGCCGAGCCTCCTTAAAACTCTGCCGTTAAAATGGGGGCGGGTTTTTCAACTCAAAA AGCGCTCAATTTTTTTCTTTTCAAAAAAAGCTGATGAGGTCGGAAAAAAGGGAGAAGAAA CCGGCACCCTCTCTGAGAGGCAACAGAAGCAGCAATTGTTTCAGCGAAAAAAGCAGCAAG GGAGGGAGTGAAGGAAAAAAGCAAAAAAGGGGGCGACACGCAAGTGCCTGTAGGGGTGAA AGGAGCAGGGACCGGCGATCTAGGGGGGGATCAGCTACAAAAGAAACTGTCACTGGGAGC GGTGCGGCCAAGGAGGAAGCAGTGCTGCCAGGCTCTGCTCCAGGGCACAGCTGGCTGGCG GCTGCCCTGTCCGCAGCAAAGGGGCACAGGCCGGGGACCGCGAGAGGTGGCAAAGTGGCA CCGGGCGCCGAGGCTGCTGAGCGCTCGCCGAGACGGCGACCGGACTGGCTGCCCCGGAAC TGCGGCGACTCTCCCTACTCAGAACTTGGCCTACGTTTCCCAGGACTCTCCCCATCTCCA GAGGCCCCCACAAAACCGGGAAAGGAAGGAAAGGACAGCGGCGGCAGCAGCTCAATGAGT GCCTACAGCAGAAAGCCTGAACGAGCTCGGTCGTAGGCGGGAAGTTCCCGGGGGGGCTGC CCAGTGCAGCCGCAATGCTGCCGCGAGCTGCCCCAGCAGTCCGGGCTCCGTAGACGCTTT CCGCATCACTCTCCTTCCTCGGGCTGCCGGGAGTCCCGGGACCTGGCGGGGCCGGCATGA CGGGCTTCTCGGGGGCCCGCCGCACGCCCGGCAGCCTCCGGAGACGCGCGCCGAGCCCGG CTCCCACGGCCTCTGAGGCTCGGCGGGGCTGCGGCTGCCTGGCGGGCGGGCTCCGGAGCT TTCCTGAGCGGCATTAGCCCACGGCTTGGCCCGGACGCGACCAAAGGCTCTTCTGGAGAA GCCCAGAGCACTGGGCAATCGTTACGACCTGTAACTTGAGGGCCACCGAACTGCTACTCC CGTTCGCCTTTGGCGATCATCTTTTAACCCTCCGGAGCACGTCAGCATCCAGCCACCGCG GCGCTCTCCCAGCAGCGGAGGACCCAGGACTATCCCTTCGGCGAGACGGATGGAAACCGA GCCCCCTGGAGGACCTGCCCCTGCAGTTCTGCCTCACACGGCTCAAGTCACCACCGTGAA CAAGGGTGGGTGAATGCCTTTTCTTCCCCCTGAATGTCTTTCCTTCCGCGGTATTTTCTG CCCCGATCTATAGTCCCTTGAGTCTCCACACACACTCCTCACAGAGATCTGTAGCGTAGG TACGTGACAGCTCTGCCTACATCTGACGTCCGGAGTCATTAACCAGGAATGTATGTGTGT CTGTGTGTCTCTCTGTGGAGTCGTCAGAATTCTTCATAGGGGTTAAGCTAAAAAAGCGAG GCGAGGAGCCCCTCTCCAATGGCTCAGTTTTGCTGAATAATCACGTGTGAATCGAGGGGC GGGCTTTTGGCAGGCAGATCTTACTAGTATTTACTACCAAGCTCTACTCCAGATTAACCA TCCCAGTCCTTCTGTCAGTCTCCGATGCCATCATGCAGCCTGGTTAGGAGCAAAGGAAAG GGGAAAAAGAAAAACGACTAATTCATCTTTTCCTGATCGTCAGGACCCTAAAGAATGGCC GAGCCTTGGGGGAACGAGTTGGCGTCCGCAGCTGCCAGGGGGGACCTAGAGCAACTTACT AGTTTGTTGCAAAATAATGTAAACGTCAATGCACAAAATGGATTTGGAAGGACTGCGCTG CAGGTTGGTATTAAGAGAGGTGGGGAAAACAAGTCAATAATGTTGCCTACGTGACCCGGG TTTCTAGATTTACAGCTTTTAAGCTTTCAGGGACATAAAATTTCACTGTTTTTAAACCTA GTTGGTTGCCATATTTTATATCTTTAAGTGGATGCAACTTCTCAAAATGACGTACTTTGA ACAAACTCCTCAAATCCAATAACATCCTTGATATCAAGTGGGGTCCAGATTTGGTCTTAG TTTTTGGAATGTTTTTGTGACGGTGGGGATTTTAAAGTAGTCAGTGTAGGGCCGAGGTTT GTTTGTTTTGTTTTGTTTTTAAAGACAGCTCTGTAAACACATTATTATGATTATTATTTG AAGTAAATACACTGCTATTAGTGGTTTTACGTACTTTGCCCCCAATAATAGACTTTAACG TTAATTTTCTTGACTACTGATGAGGGTGTTTTTCCTTCAAATGCTTCAAGTTTTGACAAA CGACCTTTCCTCGTTTGGAATGGGTGGCCTGGGCACCGGGACAGGATGTACATTTTACAG TTAATGTAATACCATCCACTCATTCAGGAGTCGGGAGGAATAAAAAGTTGAATTTTCTAA TCAGAGCTCAGCTGCAGTGTCTTTGTCTCTACGGTCATGCCGTGGTGTGCTCTAATTTTC AGTAATTAGATTTACAGGCAACAATTGACACATGTCCAGCTGCCAAGTATTGTACCTGAT AATTTTTTTCCTCTTCTGAATGTTATCATGTAACTTAGGTGAAAGGCTTAGAAACAGAAA AATGACAAAATAGTTTAAAATAGTTGCTTTATCAGAGTTCTGATGATATTCTTATGAGCT ATTCTTATTTGGAAATGCAACACTTGAAGCTGTTTTTGAAAACCCAGTGGGGAGAGGGTT TTTAGAGGGCTTTGTTTCGGTTACAAGAATTAAAAATTTAAGTGCCAAGAGATATACTAT TAACAAACAAAGTCCATACAGTCTGTACATTTTCAGTCAGAATACACTGGCCTTGCAAAA ATTTCAGTATTAAGGAAGTTTATGCACAGATACTAAATTATTTATCTTGTTATTGCTGCT ACATTAAGTAATGATTTTTTTTCCTTTTTCTACCTAGTAGTTTTGAACAGGTTTAGTGAT GATAGCAAAGTAACAAATTTAATATATTGAAAAGTTTCCTTTTGAAAACTCAAAAGATTA TATAAACTTCACAAAGAATGAACTACTTAACCCATGTTCATGATAAGATTTTACAGGATT TTTGACGAACAGGAAGACTGGGAAATTAATAATATTCTTTTAAAAAGTTTTGACAAACAT TTTTAATACAACTTTGCAATCTTGTTTATATTAAACATACTTATCAAGATACTAACACCC ACTTATTGTGGCTTAGTCCTTGTACATATAACGAAACACACACACAGAAACTGGAGTTTC AAGGCTTATTTTCAATATGTATAATCCTGACTCTGAAGTTGTGTCATAAGTCAAGAAATA ACTTTCTTCAAAACCGTTTCCAATATTGCTATTATTTTCTGTGAAAAAAGGTGAATTTTC TTCTACAATTATGTTTATTTAACTCAATTTCAAAAGCCTTTTCCACCTTCCTAGTGTACA TTTTTCTATCAGGTTAATATCAAAGGCCTTAATCGTATGTTTGCTTTACGAAGATCCAAG GTATCTGTCTCTTATTTTTCTCATTCCAGGTCCTTAAATATGACTAAATCTTTAGGGACA GTTGTGGTCGTATCAATTTTTAATAACCAAAAAGTATGTTTCATTGAAGTTCTTGAAATA TAAATTATGTATCACTGTTTACCACTGCTCCAAAGGAAGAGCTAAAAATCAACAGTTTTA TCAACAGGGGAGCTTAATATCTTGTCCATCTATGTAGTTTGCATTTACAAAATATTACTC ATTTTAAATATATTTTGTTATTTAATGTGTGATTAGATTTTTTTAAACAAACATTTAAAA AAGATAGAACGACTTTGTATTTTCCATTAGCATTTAATTTCATAAACATTGAGTGTCTAT TATACAAGATATTTATTATAAATTTAGATTATTATGGATATACCTAGATATAAATAAACC AGTGTAAATTCTGAAAATGTGTGGCATGTTAATGAAAGTAATATTTTTTCACAACTAAAT TATATGTATTTTATATTTGCATGCTGTTCTACAAGATACTTTATAAGAGACCACTGTTAG AGTGAAATATATTCAAACAATAGTAGATAATCTTTGTTATGTGAATTATTTGTATGTTGA TAGCAAGTGTTAATACCACATTCTGACTTTTAAAATGTTGGCAGTTTACAAATAGCTGTT CCTTAAATGCTTGATAATAACTGAAAAAGGAACTAACACAGGATCACCAGTTGATTATTA AATGAGCTCAAACCACAAGACAAGGCTGTCCGTGTCCCAAAACACCCATTAAATATCTTA TTTTTTCTTCTTTTGCTCATTTGAAAATCAGGAGGCTTGTCAGAACTTTGAGAAACAGTA TATAATGTAATAGGGTGACTATTTCATTATTTTCAAGAACAGTTGTCCTACAATAATTTC CTACTGTGATACAAGGCATATCAGGAACTTAGTTTTATATAAATTGATATCATAAGCAAT TTAGAACACTGTGGCTTATTTAACACCTTAATAATCAGTACTGTTTTGTAACTTAAAATG AAGGATTCTAAACATTGAATACACCTAGTAGCCAATATTAAATAACTTGCAAATAAAAAA TATTTTTAAGAAATGCTTGGAAATTTGGAGCTATATCTATTTGGAGGGAACTTGTAAAAA TTGATCATTTAAGAAAATATCAGGCCTGGATTTTTAAAACATCATTTTTACACTCACTCA TGGAGTTGGTTTAGAGAAACTCAACATCCTTATTTGTTTGCAGTAGCTATTTAGAAAATA AAGTTTAACCACATATGATTTTCTAGAATTAATACCACAGGCACATTTTATGAGCATGAA CAATCAAACAGAAGGAGACTCTTATTTAAATCCCAAATTCCATTTCTGTTATTTTAATAA ATTCGTGAAATTACACAACTCTTCATGGAACATAGAGAACAGAATTGTTAGCAAATGCTA TACATGTTGCACAAATTCTATCTTATTGATCAATTTATCCTACTTTTGGGCCCATTTAAG ACGTTCCATCATAGAAGCTCAATTTTTAGAAGTTGTCTTCTACTTTCACCTACTAGCACT TTTCTGCATTTGACCCCTTCAAGCCCCATCCTATGGGTCTTCCGCAAGAACTCCATCAAA AATAAATAGTTACATAAATGGAAGGACAGGCAGATATTTTAAAATATCTCTGTAGCATAT GCACTTGAAGGATTCTACCATTTCTACTTCTTTTCCAGGTTATGAAACTTGGAAATCCCG AGATTGCCAGGAGACTGCTACTTAGAGGTGCTAATCCCGATTTGAAAGACCGAACTGGTT TCGCTGTCATTCATGATGCGGCCAGAGCAGGTTTCCTGGACACTTTACAGACTTTGCTGG AGTTTCAAGCTGATGTTAACATCGAGGATAATGAAGGGAACCTGCCCTTGCACTTGGCTG CCAAAGAAGGCCACCTCCGGGTGGTGGAGTTCCTGGTGAAGCACACGGCCAGCAATGTGG GGCATCGGAACCATAAGGGGGACACCGCCTGTGATTTGGCCAGGCTCTATGGGAGGAATG AGGTTGTTAGCCTGATGCAGGCAAACGGGGCTGGGGGAGCCACAAATCTTCAATAAACGT GGGGAGGGCTCCCCCACGTTGCCTCTACTTTATCAATTAACTGAGTAGCTCTCCTGACTT TTAATGTCATTTGTTAAAATACAGTTCTGTCATATGTTAAGCAGCTAAATTTTCTGAAAC TGCATAAGTGAAAATCTTACAACAGGCTTATGAATATATTTAAGCAACATCTTTTTAACC TGCAAAATCTGTTCTAACATGTAATTGCAGATAACTTTGACTTTCTTCTGAATATTTTAT CTTTCCTTGGCTTTTCCCTTGCTTCCCCTTTTGCCAATCTCAACACCCAAGTTGAAGACT TTGTTTTTAAAATGGTTTGTCCTGATGCTTTTGTCTAATTAAAACACTTTCAAAACAGGA CAA OMIM ID 603369