Entrez gene ID | | 10311 |
Official gene symbol | | DSCR3 |
Full name | | Down syndrome critical region gene 3 |
Aliases | | ,DCRA,DSCRA,MGC117385, |
Gene summary | | The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q22.2 |
Gene position | | 38639833 - 38595726 Map Viewer |
Gene orientation | | minus |
Gene size | | 44108 bp |
Gene sequence |
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OMIM ID | | 605298 |
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