Entrez gene ID | | 10326 |
Official gene symbol | | SIRPB1 |
Full name | | signal-regulatory protein beta 1 |
Aliases | | ,CD172b,DKFZp686A05192,FLJ26614,SIRP-BETA-1, |
Gene summary | | The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20p13 |
Gene position | | 1600689 - 1545029 Map Viewer |
Gene orientation | | minus |
Gene size | | 55661 bp |
Gene sequence |
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OMIM ID | | 603889 |