Entrez gene ID | | 10397 |
Official gene symbol | | NDRG1 |
Full name | | N-myc downstream regulated 1 |
Aliases | | ,CAP43,CMT4D,DRG1,GC4,HMSNL,NDR1,NMSL,PROXY1,RIT42,RTP,TARG1,TDD5, |
Gene summary | | This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q24.3 |
Gene position | | 134309547 - 134249414 Map Viewer |
Gene orientation | | minus |
Gene size | | 60134 bp |
Gene sequence |
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OMIM ID | | 605262 |
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