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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PIAS3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10401
Official gene symbolPIAS3
Full nameprotein inhibitor of activated STAT, 3
Aliases,FLJ14651,ZMIZ5,
Gene summaryThis gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q21
Gene position145575988 - 145586546  Map Viewer
Gene orientationplus
Gene size10559 bp
Gene sequence
OMIM ID605987