Entrez gene ID | | 10407 |
Official gene symbol | | SPAG11B |
Full name | | sperm associated antigen 11B |
Aliases | | ,EDDM2B,EP2,EP2C,EP2D,HE2,HE2C,MGC61846,SPAG11, |
Gene summary | | This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8p23-p22 |
Gene position | | 7321192 - 7305276 Map Viewer |
Gene orientation | | minus |
Gene size | | 15917 bp |
Gene sequence |
| |
OMIM ID | | 606560 |
|