| Entrez gene ID | | 10435 |
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| Official gene symbol | | CDC42EP2 |
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| Full name | | CDC42 effector protein (Rho GTPase binding) 2 |
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| Aliases | | ,BORG1,CEP2, |
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| Gene summary | | CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq] |
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| Location | | Chromosome: 11 Locus: 11q13 |
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| Gene position | | 65082331 - 65089900 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 7570 bp |
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| Gene sequence |
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| OMIM ID | | 606132 |
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