Entrez gene ID | | 1045 |
Official gene symbol | | CDX2 |
Full name | | caudal type homeobox 2 |
Aliases | | ,CDX-3,CDX3, |
Gene summary | | The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM] |
Location | | Chromosome: 13 Locus: 13q12.3 |
Gene position | | 28543317 - 28536278 Map Viewer |
Gene orientation | | minus |
Gene size | | 7040 bp |
Gene sequence |
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OMIM ID | | 600297 |
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