Entrez gene ID | | 10450 |
Official gene symbol | | PPIE |
Full name | | peptidylprolyl isomerase E (cyclophilin E) |
Aliases | | ,CYP-33,MGC111222,MGC3736, |
Gene summary | | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p32 |
Gene position | | 40204517 - 40229586 Map Viewer |
Gene orientation | | plus |
Gene size | | 25070 bp |
Gene sequence |
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OMIM ID | | 602435 |