| Entrez gene ID | | 10457 |
|
| Official gene symbol | | GPNMB |
|
| Full name | | glycoprotein (transmembrane) nmb |
|
| Aliases | | ,HGFIN,NMB, |
|
| Gene summary | | The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
|
| Location | | Chromosome: 7 Locus: 7p15 |
|
| Gene position | | 23286316 - 23314729 Map Viewer |
|
| Gene orientation | | plus |
|
| Gene size | | 28414 bp |
|
| Gene sequence |
| |
|
| OMIM ID | | 604368 |
|
|
|
