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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CREB3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 10488 Official gene symbol CREB3 Full name cAMP responsive element binding protein 3 Aliases ,LUMAN,LZIP,MGC15333,MGC19782, Gene summary This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined. Location Chromosome: 9   Locus: 9pter-p22.1 Gene position 35732317 - 35737005  Map Viewer Gene orientation plus Gene size 4689 bp Gene sequence >CREB3:35722317..35727005:Length=4689 GGAAGCGAGGGTGCGGCGCAATCCGGAGAGGACGCCAGGACGACGCCCGAGTTCCCTTTC AGGCTAGAACTCTTCCTTTTTCTAGCTTGGGGTAGAAGGCGGAGCCGGAGCCCCGGAACC CCCGCCCTCGGGGTGCGAGGCGGCAGCAGGGCCGTCCCCTACATTTGCATAGCCCCTGGG ACGTGGCGCTGCACCCAAGCCTCTTCTCAGTTGGAGGGAACTCCAAGTCCCACAGTGCCA CGGGGTGGGGTGCGTCACTTTCGCTGCGTTGGAGGCTGAGGAGAATTGAGCCTGGGAGGC GGGTCCGGAGAGGGCTATGGAAAGCCGCCGGCGGGGAATCCCGGCCGTAGAGGGACAGTG GATAGGTGCCCGAGGCCTACAGCTGGCCTGGGGCTCGTGTCTGGGCTTCGGACGTTGGGG CCCGGTGGCCCACCCTTTCCGTAGTTGTCCCAAATGGAGCTGGAATTGGATGCTGGTGAC CAAGACCTGCTGGCCTTCCTGCTAGAGGAAAGTGGAGATTTGGGGACGGCACCCGATGAG GCCGTGAGGGCCCCACTGGACTGGGCGCTGCCGCTTTCTGAGGTAGGTTGGGGTTCTGAC TGGGGAAAGCGTGGGATGTCCATGAAGTCAGGTGATGGTGATAAGGTCAAGGCCTGTTCA TTGGAACCCTGCGCAGGTACCGAGCGACTGGGAAGTAGATGATTTGCTGTGCTCCCTGCT GAGTCCCCCAGCGTCGTTGAACATTCTCAGCTCCTCCAACCCCTGCCTTGTCCACCATGA CCACACCTACTCCCTCCCACGGGAAACTGTCTCTATGGATCTAGGTGAGTCTGAAATAAG TTTGCGGGGAGGACAGGGTTCATGGGCCTGGCTATTCATACTTTCCCTTTTGCAGAGAGT GAGAGCTGTAGAAAAGAGGGGACCCAGATGACTCCACAGCATATGGAGGAGCTGGCAGAG CAGGTACTTGACTTGATTTTCAGGAGATTACTCTCACATTCCCCAGGTGGGGGCAGGATT CCCCATTCCTCTCTGACATCCCCATGCAACTGCCGTCCACTTTCTTGTTACCCTAGGAGA TTGCTAGGCTAGTACTGACAGATGAGGAGAAGAGTCTATTGGAGAAGGAGGGGCTTATTC TGCCTGAGACACTTCCTCTCACTAAGGTAAGACTCTCATTGGTTGAACAAAGGCTGAAAA GGGATTAAAAGTCCCAAGTAGGCAAATTCTGTTAACTTTATATCAATAACTTTAAAAAAG GATTGAGGTGAGAAACTTAGTAGATTTATTGCTAATAGGAAGTTGAGGCAGGTACACAAT ATGCCAGATGCAAGGGCAGATCCTCGTTTTTGTTGGGCTTATACAAATTTTGGTGTTCTG TTAAAAAAATAACTCAAAATTATCAGTGCAACATTAGTATTGGGCCTTGGAAAGGACTGT GTAAGTGAAGGGCCTTGACACTTCGTTGGCTTCATAGTAATCCACCTCTTGCTGAATGGT AGAACTGTTTAGAGAGTTCAACAGGGTTGGACTAAGCAGTACATGAATAAATGTAAAATC CTTAGTTTTCAGTTTTAAGCAATGAGTGGCAACTTCACAAGCAGAGTACTGGGGTACTAT GATGAAATCAGTGCTCATTAATAGAAAGGTTACAGGAATATATATATATTTTTTGACAAG GTCTTGCTCTGTTGCCCAGGCTGGAGTGCACTGATGTGATCATGGCTCACTGCAGCCTTG ACTTTCTGGGCTTAGGTGATTCTCCCACCTCAGCCTCCCGAGTAGCTGAGACTACAGGTG CACACTACCCTGCCCGGCAATTTTTTTTTTGGTATTTTTAGTAGAAATGGGGTTTTGCCT TGTTGCCAGGCTGGTCTCGAACTCCTGGGCTCAAGTGATCTACCCACCTTGGCCTCCCAA AGTGAAGAATTTTAATTTCTTCAAAGTACAAGATGAGTCAGCAGTGTGATGTGGCTACTA AGAAAGTTCATGGGATTTGGAAACTGTAGCAATAGAGTTATTGTCTCTACAAGTCACTCT CTTGCTTTCCTTGATACTGGCTAGAGCACATCTTTGACAGATACTAAGAGGATGCAGTCT ATCCTGAGAAGATGAGTTAAAAATTTTGTCTTTTTTTTTTTCTTTAAGCTCTGAGGAAAT GTTAAGTGCCTTAAAATAGCTAAACAGGGTTTATTCTATTTGGCCCCAGAGATACTAGGT AAGTCCAACGGATAGAAATTATAAGGAGGCAGCTGTTGGTTCAGGATAAGGAAGTTTTTA TTTGCTTGTTTGAAGACAGGTTCTTGCTTTATTGCCCAGGTTGGAGAATAGTGGCGAGAT CATGGCTCACTACAGCTTCAACCTCTCAGGCTCAAGTGATCCTCCTTCCTCAGTCTCCTG AGTAGCAGGGACCACAGGCATGTGCCACCACACCCGGCTAATTTTTTATTTTTAGTAGAG ACAAGGTCTCACTATGTTGCTCAGGCTGGTCTCAAACTCCTGGGCTCAACCGGTCCTCCT GTCTTAGCTCCCCAAAGTGTTGGGATTACAGGCATGAGCCACGTCGCCTGAATACTGCCC GACCAGTTTTTTTTTTAATAGTTTAAAATGGTCTGGCTTGTTAGGGTTAACACCTGGTCC GTGGAGGCATTCAGAAAGAATCTGAATGCCTGTTGGTCAGGGAAGCTGTAGAAGGGATTT CTGTATTGGAAAGAGATTGATCTCAGTTGCGTTTCAACTCCTTTTTCTAGAGTTCCTCTA ATGATATCCCTTTCCCTGTTTCCTTTCAGACAGAGGAACAAATTCTGAAACGTGTGCGGA GGAAGATTCGAAATAAAAGATCTGCTCAAGAGAGCCGCAGGAAAAAGAAGGTGTATGTTG GGGGTTTAGAGAGCAGGTATGAAAGGGAGAGGGACTCTGTTGTAAGTATTAGGTTTTTGA AGGGAGGATACAGGCCATATCCCCGTATCTTTGTTATTTCCCCCAGGGTCTTGAAATACA CAGCCCAGAATATGGAGCTTCAGAACAAAGTACAGCTTCTGGAGGAACAGAATTTGTAAG TATCCCTCCAAACCATTCCCTTCCTATGCCCCTCATTTAATGCTTTCTCACTCTTTCCCC TGCCCTACACTTGATTTCTAACTGGGCAGCTGCCTTCACTAGGTCTCTGATTCCAAGAAG CTCCCAGTAGTGAGGAATACATTTACAAGTAACTAAGAATAAGTTAAGTACCAAGAAAAA GAAAGGGGGTAAGAAAGACGTCATGGGCTTTCATAGTAGTTAGGATTCTGGGGTTGGGTT GGGAAAGCATTCTAGGCAGAGAGAAAGCATCCTAGGCAAGAGGACTAGTCCAGCATAGTC ATCTTGGGCTGGAACTCTTAACACACATGAGCTGGGACAGAAGGTAGAGAACATAGAAAA TGCCTGGTGAGGATTATGTGCATAGCTGATCAGACAGTGGGGAACGACTGATGATATTCG CAAAGGAGGTTAAGTCCTGGCAGAGTTTTTTTGTTTTGTTTTGTTTTTGCTTTTTGTTGT TGTTGTTGTTTTAATGAGGAACTTCAGGCATTTTGTCCAGAGAGGAAGAAGTCGTTTGCA AAAATAGAATGAAAAGTAAGAGAGAGGATCCAGTGCAGAGATGGAGGAGGTGGCCTGAAC AGGAGTTTCACTGTGTCTCAGGATGCTAGGCCAGGGGATGCTCACTATTGGCCCCTCTCT TCCTCTAGGTCCCTTCTAGATCAACTGAGGAAACTCCAGGCCATGGTGATTGAGATATCA AACAAAACCAGCAGCAGCAGCACCTGCATCTTGGTGAGGATGGTGATGAGGGGAGAAATC CTTTTCTCAGTTGGTGGGGACAGGGCAATCCAGAGCCCTTCTTCATCTCCTTTTTCCTGT GCTCTAGGTCCTACTAGTCTCCTTCTGCCTCCTCCTTGTACCTGCTATGTACTCCTCTGA CACAAGGGGGAGCCTGCCAGCTGAGCATGGAGGTAAGAGGCTTAAGGATAGCTCTCAGAC AGGGCAAGGGGAGAGGTCTGGGTTGGCCTCTGAAGATTCTTTGTCTCCTCAGTGTTGTCC CGCCAGCTTCGTGCCCTCCCCAGTGAGGACCCTTACCAGCTGGAGCTGCCTGCCCTGCAG TCAGAAGTGCCGAAAGACAGCACACACCAGTGGTTGGACGGCTCAGACTGTGTACTCCAG GCCCCTGGCAACACTTCCTGCCTGCTGCATTACATGCCTCAGGCTCCCAGTGCAGAGCCT CCCCTGGAGTGGCCATTCCCTGACCTCTTCTCAGAGCCTCTCTGCCGAGGTCCCATCCTC CCCCTGCAGGCAAATCTCACAAGGAAGGGAGGATGGCTTCCTACTGGTAGCCCCTCTGTC ATTTTGCAGGACAGATACTCAGGCTAGATATGAGGATATGTGGGGGGTCTCAGCAGGAGC CTGGGGGGCTCCCCATCTGTGTCCAAATAAAAAGCGGTGGGCAAGGGCTGGCCGCAGCTC CTGTGCCCTGTCAGGACGACTGAGGGCTCAAACACACCACACTTAATGGCTTTCTGGGTC TTTTATTTGTACCCATGTGTCTGTCACACCATGAATGTACCTGGGGAAATCAACTGACCT CCCTGAACATTTCACGCAGTCAGGGAACAGGTGAGGAAAGAAATAAATAAGTGATTCTAA TGCTGCCTA OMIM ID 606443